Wk 5 Integumentary System Flashcards
Skin is called?
Cutaneous
Largest organ
Cutaneous has 2 main regions
°Epidermis
°Dermis
Epidermis is made from what type of tissue?
Keratinized stratified Squamous Epithelial (waterproof & protection)
Dermis is made from what type of tissue?
Loose CT & dense irregular CT
Skin structure
(6 things)
° accessory structures
° sensory receptors
° arrector pili muscle
° epidermis
° dermis
° hypodermis
Skin structure
Accessory structures:
° sweat glands
° sebaceous glands
° hairs
° nails
Skin structure
Sensory receptors:
detects heat, cold, pain, and pressure
Skin structure
Arrector pili muscle:
Small bands of SMC (smooth muscles) associate with hair
Skin structure
Epidermis:
°avascular (no blood flow)
° transport of O2 and nutrients by diffusion
Skin structure
Dermis:
° vascular (has blood vessels)
Skin structure
Hypodermis:
° superficial fascia/ subcutaneous fat is deep in the dermis
°not part of skin, anchors skin to deeper structures
° loose CT and adipose
° vascular (blood vessels)
Integumentary system
function:
(5 functions)
° Protect
° sensation
° thermoregulation
° excretion
° synthesis
Integumentary system
function: protection
°Mechanical trama
° pathogens
° environment
Integumentary system
function: sensation
Preceive changes in the body’s internal / external environment
Integumentary system
function: thermoregulation
Uses negative feedback loops to maintain stable internal temperature
(Muscles and metabolism)
Integumentary system
function: excretion
Process where waste products and toxins are eliminated (sweat)
Integumentary system
function: synthesis
Making Vitmin D and calcitriol by using UV rays (sunlight)
Body temperature above normal:
Stimulus
Body too hot due to weather or sickness
Body temperature above normal:
Receptors
Thermoreceptors detect an increase in body temperature
Body temperature above normal:
Control center
Thermoregulatory center in the brain (hypothalamus) acts as a thermostat
Body temperature above normal:
Effector / response
The control center stimulates sweating and vasodilation (VD) of vessels in dermis
Body temperature above normal:
Homeostasis and negative feedback
° body temperature returns to normal
° thermoregulatory center decreases output to glands and vessels
Body temperature below normal:
Stimulus
Body temperature drops below normal range, too cold
Body temperature below normal:
Receptors
Thermoreceptors detect the drop in temperature and relya the info to the hypothalamus
Body temperature below normal:
Control center
Thermoregulatory center in the brain (hypothalamus) acts as a thermostat
Body temperature below normal:
Effector / response
Blood vessels in dermis vasoconstrict, decrease sweating, increase shivering
Body temperature below normal:
Homeostasis and negative feedback
° body temperature returns to normal
° thermoregulatory center decreases output to vessels and muscles (reduce shivering)
Lose heat:
Sweating and vasodilation
Conserve heat:
Decrease sweating and vasconstrict
Produce heat:
Muscle contraction
Calcitriol
Necessary for absorption of Ca++ by sunlight
Ca++
Necessary for nerve function, muscle contraction, bone
Epidermis
° most superficial layer (surface)
° composed of mostly keratinocytes
° produces keratin (protein)
Epidermis layers:
(There are 5)
- Stratum corneum
- Stratum lucidum
- Stratum granulosum
- Stratum spinosum
- Stratum basale
Epidermis:
Stratum corneum
° Outer most layer
° Mostly dead cells
° made of several layers
Epidermis:
Stratum Lucidum
° thick skin only (palms and soles of feet)
° clear layer (dead keratinocytes)
Epidermis:
Stratum Granulosum
° 3 to 5 layers of cells
° keratin filled cells (water resistance)
Epidermis:
Stratum spinosum
° bit of mitosis
° metabolically active and mitotically active
Epidermis:
Stratum basale
° (stratum germinativum)
° Deepest layer.
° most mitosis
° most metabolically active and mitotically active
Keratinocytes life cycle
° Made by mitosis in the stratum basale layer
° Get pushed up to the stratum corneum as they age and die
° Mitosis happens mostly at night.
Other Cells of the epidermis (3 of them)
° Dendritic (langerhans) cells
° Merkel cells
° melanocytes
Dendritic (langerhans) cells
° Located in stratum spinosum
° Phagocytes of the immune system
° Protect skin and deeper tissues from pathogens.
Merkel cells
° Located in stratum basale
° Sensory receptors detect light touch.
° Fingertips, lips, and at base of hair.