White matter tracts Flashcards

1
Q

There are _ pairs of spinal nerves;
_ cervical
_ thoracic
_ lumbar
_ sacral
_ coccygeal

A

There are 31 pairs of spinal nerves;
8 cervical
12 thoracic
5 lumbar
5 sacral
1 coccygeal

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2
Q

The _ root contains axons of somatic motor nerves

A

The ventral root contains axons of somatic motor nerves
* These innervate skeletal muscles

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3
Q

The _ root contains axons of somatic sensory nerves

A

The dorsal root contains axons of somatic sensory nerves
* These convey sensation (pain, touch, temperature)

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4
Q

The spinal nerve carries _ type of information

A

The spinal nerve carries somatic and visceral motor & sensory information
* The ventral and dorsal roots unite to form a spinal nerve

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5
Q

The cell bodies of somatic motor nerves are found in the [location of spinal nerve]

A

The cell bodies of somatic motor nerves are found in the ventral horn

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6
Q

The cell bodies of somatic sensory nerves are found in the [location of spinal nerve]

A

The cell bodies of somatic sensory nerves are found in the dorsal root ganglion

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7
Q

Sympathetic nerves originate in the [gray matter location]

A

Sympathetic nerves originate in the lateral horns of the gray matter
* Only between T1-L2

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8
Q

The lateral horn of gray matter is found in [spinal cord regions]

A

The lateral horn of gray matter is found in T1-L2

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9
Q

Sympathetic nerves exit the spinal cord via _ before entering _

A

Sympathetic nerves exit the spinal cord via ventral root before entering sympathetic chain
* These are visceral motor nerves

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10
Q

The cell body of visceral motor nerves is in the [spinal nerve region]

A

The cell body of visceral motor nerves is in the lateral horn

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11
Q

The cell body of visceral sensory nerves is found in the [region]

A

The cell body of visceral sensory nerves is found in the dorsal root ganglion

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12
Q

Most spinal nerves contain 4 distinct types of nerves:

A

Most spinal nerves contain 4 distinct types of nerves:
1. Somatic motor
2. Somatic sensory
3. Visceral motor
4. Visceral sensory

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13
Q

The _ rami of spinal nerves combine to form nerve plexuses

A

The ventral rami of spinal nerves combine to form nerve plexuses
* Cervical, brachial, lumbar, and sacral plexuses
* Intercostal nerves don’t form a plexus

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14
Q

Cervical plexus forms from [spinal cord rami] and innervates structures within the neck (and diaphragm)

A

Cervical plexus forms from C1-C4 and innervates structures within the neck (and diaphragm)

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15
Q

Brachial plexus forms from [spinal cord rami] and innervates the upper limb/shoulder girdle

A

Brachial plexus forms from C5-T1 and innervates the upper limb/shoulder girdle

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16
Q

Lumbar plexus forms from [spinal cord rami] and combines with the sacral plexus

A

Lumbar plexus forms from T12-L4 and combines with the sacral plexus

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17
Q

Sacral plexus forms from [spinal cord rami] and combines with the lumbar plexus to innervate the lower limb and perineum

A

Sacral plexus forms from L4-S4 and combines with the lumbar plexus to innervate the lower limb and perineum

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18
Q

Sensory information from the thumb and lateral arm returns to the spinal cord via the _ spinal nerve and enters the respective spinal cord segment

A

Sensory information from the thumb and lateral arm returns to the spinal cord via the C6 spinal nerve and enters the respective spinal cord segment

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19
Q

Neck/shoulder dermatome:

A

Neck/shoulder dermatome: C3,4,5

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20
Q

Thumb/lateral arm dermatome:

A

Thumb/lateral arm dermatome: C6

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21
Q

Middle finger dermatome:

A

Middle finger dermatome: C7

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22
Q

Little finger/medial arm dermatome:

A

Little finger/medial arm dermatome: C8

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23
Q

Nipple dermatome:

A

Nipple dermatome: T4

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24
Q

Umbilicus dermatome:

A

Umbilicus dermatome: T10

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25
Q

Perineum/Perianal dermatome:

A

Perineum/Perianal dermatome: S2,3,4

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26
Q

Anterior knee/big toe dermatome:

A

Anterior knee/big toe dermatome: L4

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27
Q

Middle toes dermatome:

A

Middle toes dermatome: L5

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28
Q

Little toe/lateral foot dermatome:

A

Little toe/lateral foot dermatome: S1

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29
Q

[Spinal cord segment] : abduction of the shoulder

A

C5 : abduction of the shoulder

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30
Q

[Spinal cord segment] : flexion of elbow

A

C6 : flexion of elbow

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31
Q

[Spinal cord segment] : extension of elbow

A

C7 : extension of elbow

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32
Q

[Spinal cord segment] : extension of wrist/fingers

A

C7 : extension of wrist/fingers

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33
Q

[Spinal cord segment] : flexion of wrist/fingers

A

C8 : flexion of wrist/fingers

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34
Q

[Spinal cord segment] : hip flexion

A

L2 : hip flexion

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35
Q

[Spinal cord segment] : hip adduction

A

L3 : hip adduction

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36
Q

[Spinal cord segment] : knee extension

A

L4 : knee extension

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37
Q

[Spinal cord segment] : ankle dorsiflexion

A

L5 : ankle dorsiflexion

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38
Q

[Spinal cord segment] : ankle plantarflexion

A

S1 : ankle plantarflexion

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39
Q

The spinal cord ends at [vertebral levels]

A

The spinal cord ends at L1 or L2

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40
Q

Cervical nerves C1-C7 traverse through their corresponding intervertebral foramen _ to the vertebra

A

Cervical nerves C1-C7 traverse through their corresponding intervertebral foramen superior to the vertebra

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41
Q

All spinal nerves below _ traverse inferior to the vertebra

A

All spinal nerves below C8 traverse inferior to the vertebra
* C8 and below will go below

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42
Q

The lateral horn is the location of _ cell bodies

A

The lateral horn is the location of preganglionic sympathetic nerve cell bodies

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43
Q

The white matter is divided into (3) columns:

A

The white matter is divided into (3) columns:
1. Dorsal columns (posterior)
2. Ventral columns (anterior)
3. Lateral columns

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44
Q

The _ is a central region of the spinal cord where axons that convey pain and temperature can cross over to the other side of the cord

A

The anterior commissure is a central region of the spinal cord where axons that convey pain and temperature can cross over to the other side of the cord

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45
Q

Dorsal columns convey [type information]

A

Dorsal columns convey ascending sensory nerves
* Convey touch, pressure, vibration, proprioception
* “Be sensative and stay P.C.” = posterior column

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46
Q

Anterior columns convey [type information]

A

Anterior columns convey descending motor nerves to control voluntary movements
* Anterior corticospinal tract

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47
Q

Lateral columns convey [type information]

A

Lateral columns convey descending motor nerves to control voluntary movements
* Lateral corticospinal tract

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48
Q

Lateral columns convey [type information]

A

Lateral columns convey ascending sensory nerves
* Spinothalamic tracts

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49
Q

[Tract] detects mechanical-like stimuli (pressure, vibration, fine touch, proprioception)

A

Dorsal column medial lemniscus detects mechanical-like stimuli (pressure, vibration, fine touch, proprioception)

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50
Q

[Tract] detects pain and temperature

A

Spinothalamic detects pain and temperature
* Our nervous system separates mechanical stimuli from pain/temperature

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51
Q

Pain and temperature information crosses over in the _

A

Pain and temperature information crosses over in the spinal cord

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52
Q

Mechanical sensations cross over in the _

A

Mechanical sensations cross over in the caudal medulla

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53
Q

Dorsal column medial lemniscus tract conveys mechanical information to the [brain region]

A

Dorsal column medial lemniscus tract conveys mechanical information to the primary somatosensory cortex
* Fine touch, vibration, pressure, proprioception

54
Q

The DCML involves [#] neurons

A

The DCML involves 3 neurons

55
Q

DCML tract:
Neuron 1 cell body: [location]
Neuron 2 cell body: [location]
Neuron 3 cell body: [location]

A

DCML tract:
Neuron 1 cell body: dorsal root ganglion
Neuron 2 cell body: caudal medulla
Neuron 3 cell body: thalamus

56
Q

Neuron 1 in the DCML pathway senses mechanical sensation in our lower body and enters the spinal cord via the _ and ascends to the _

A

Neuron 1 in the DCML pathway senses mechanical sensation in our lower body and enters the spinal cord via the dorsal column (gracile tract) and ascends to the medulla

57
Q

In the [medullary nucleus] neuron 1 synapses on neuron 2 (DCML)

A

In the gracile/cuneate nucleus neuron 1 synapses on neuron 2 (DCML)

58
Q

Which neuron of the DCML decussates?

A

Neuron 2 of DCML decussates in the medulla

59
Q

Neuron 2 (DCML) begins in the _ and ascends to the _

A

Neuron 2 (DCML) begins in the gracile/cuneate nucleus and ascends to the VPL nucleus of the thalamus
* Decussates in medulla and ascends via medial lemniscus

60
Q

The second synapse of the DCML occurs in the _

A

The second synapse of the DCML occurs in the VPL of the thalamus

61
Q

Neuron 3 (DCML) begins in the _ and travels to the _

A

Neuron 3 (DCML) begins in the VPL and travels to the primary sensory cortex
* Traversing the internal capsule

62
Q

Neuron 1 in the DCML pathway senses mechanical sensation in our upper body and enters the spinal cord via the _ and ascends to the _

A

Neuron 1 in the DCML pathway senses mechanical sensation in our upper body and enters the spinal cord via the dorsal column and ascends to the cuneate nucleus

63
Q

Spinothalamic pathway carries [information] to the [brain region]

A

Spinothalamic pathway carries pain and temperature to the primary somatosensory cortex

64
Q

The spinothalamic pathway involves [#] neurons

A

The spinothalamic pathway involves 3 neurons

65
Q

Spinothalamic pathway:
Neuron 1 cell body: [location]
Neuron 2 cell body: [location]
Neuron 3 cell body: [location]

A

Spinothalamic pathway:
Neuron 1 cell body: DRG
Neuron 2 cell body: dorsal horn
Neuron 3 cell body: thalamus

66
Q

When/Where does the first synapse of ST occur?

A

Pain/temp enters the spinal cord and immediately synapses in dorsal horn

67
Q

The ST tract decussates in the [location]

A

The ST tract decussates in the spinal cord

68
Q

Neuron 2 (ST tract) decussates in the spinal cord, ascends via the spinothalamic tract to the [location]

A

Neuron 2 (ST tract) decussates in the spinal cord, ascends via the spinothalamic tract to the VPL of the thalamus

69
Q

The second synapse of the ST tract occurs in [location]

A

The second synapse of the ST tract occurs in VPL

70
Q

Neuron 3 (ST tract) travels from _ to _

A

Neuron 3 (ST tract) travels from VPL to primary sensory cortex

71
Q

Another name for spinothalamic tract is _

A

Another name for spinothalamic tract is anterolateral system

72
Q

The site of the spinal cord where spinothalamic tracts decussate is the _

A

The site of the spinal cord where spinothalamic tracts decussate is the anterior commissure

73
Q

Upper motor neurons originate in the _ and synapse on a lower motor neuron

A

Upper motor neurons originate in the motor cortex and synapse on a lower motor neuron

74
Q

Lower motor neurons originate in the _ and project directly onto the muscle

A

Lower motor neurons originate in the ventral horn of spinal cord and project directly onto the muscle
* Some lower motor neurons will actually be in the brainstem (cranial nerve nuclei) and innervate head/neck

75
Q

UMN descend through the [portion] of the internal capsule

A

UMN descend through the posterior limb of the internal capsule

76
Q

90% of UMN will decussate in the _ and form the _ tracts

A

90% of UMN will decussate in the caudal medulla and form the lateral corticospinal tracts

77
Q

10% of UMN cross over in the _ and form the _ tracts

A

10% of UMN cross over in the anterior commissure and form the ventral (anterior) corticospinal tracts

78
Q

LMNs of the lateral corticospinal tracts innervate [muscles]

A

LMNs of the lateral corticospinal tracts innervate limb muscles
* For complex motor activities

79
Q

LMNs of the ventral corticospinal tracts innervate [muscles]

A

LMNs of the ventral corticospinal tracts innervate truncal muscles
* Core body muscles for postural control

80
Q

UMNs of the corticobulbar tracts traverse through the [portion] of the internal capsule

A

UMNs of the corticobulbar tracts traverse through the genu of the internal capsule

81
Q

Corticobulbar tracts synapse on _

A

Corticobulbar tracts synapse on cranial nerve motor nuclei

82
Q

Why are many cranial nerve motor functions preserved in stroke patients?

A

Many cranial nerve motor nuclei receive UMN input from both cortices
* CN XII only receives UMN from the contralateral motor cortex

83
Q

[3 CNs] do not receive corticobulbar tracts; they are controlled by the frontal eye fields

A

CN III, IV, VI do not receive corticobulbar tracts; they are controlled by the frontal eye fields

84
Q

The upper half of the face is controlled by the [CN nucleus] and receives UMN from _

A

The upper half of the face is controlled by the upper facial motor nucleus and receives UMN from both motor cortices

85
Q

The lower half of the face is controlled by the [CN nucleus] and receives UMN from _

A

The lower half of the face is controlled by the lower facial motor nucleus and receives UMN from contralateral motor cortex

86
Q

When a patient suffers from UMN damage to the facial nerve the [nucleus] remains functional

A

When a patient suffers from UMN damage to the facial nerve the upper facial nucleus remains functional
* Therefore the upper facial muscles continue to function, while lower muscles are paralyzed

87
Q

Rubrospinal tract: [function]

A

Rubrospinal tract: facilitates arm movements
* Augments the lateral corticospinal tracts
* E.g. flexor muscles of the upper limb

88
Q

The rubrospinal tract runs from the _ to the _

A

The rubrospinal tract runs from the red nucleus (midbrain) to the cervical spinal cord

89
Q

The tectospinal tract: [function]

A

The tectospinal tract: influences reflex head movements in response to visual and auditory systems

90
Q

The tectospinal tract runs from the _ to the _

A

The tectospinal tract runs from the colliculi (midbrain) to the cervical spinal cord
* Also called the colliculospinal

91
Q

Reticulospinal tract: [function]

A

Reticulospinal tract: helps activate muscles involved in posture/balance/equilibrium

92
Q

The reticulospinal tract runs from the _ to the _

A

The reticulospinal tract runs from the reticular formation to the lower spinal cord

93
Q

Vestibulospinal tract: [function]

A

Vestibulospinal tract: controls muscles which respond to changes in gravity and balance

94
Q

The lateral and medial vestibular nuclei receive input from the _

A

The lateral and medial vestibular nuclei receive input from the semicircular canals
* Information about head and body position

95
Q

Inputs to the lateral vestibular nuclei are relayed (ipsilaterally/contralaterally)

A

Inputs to the lateral vestibular nuclei are relayed ipsilaterally
* Via the lateral vestibulospinal tracts

96
Q

Inputs to the _ vestibular nuclei are relayed bilaterally into the cervical spinal cord

A

Inputs to the medial vestibular nuclei are relayed bilaterally into the cervical spinal cord
* Via the medial vestibulospinal tracts

97
Q

The lateral vestibulospinal tracts function to _

A

The lateral vestibulospinal tracts function to activate antigravity muscles to maintain balance
* E.g. activating extensor muscles
* We call this vestibulospinal reflex

98
Q

The medial vestibulospinal tracts function to _

A

The medial vestibulospinal tracts function to stabilize head movements
* Vestibulocervical reflex

99
Q

Mechanical stimuli ascends (ipsilaterally/contralaterally) in the spinal cord

A

Mechanical stimuli ascends ipsilaterally in the spinal cord

100
Q

Pain and temperature stimuli ascend (ipsilaterally/contralaterally) in the spinal cord

A

Pain and temperature stimuli ascend contralaterally in the spinal cord

101
Q

Many cranial nerve motor nuclei receive bilateral corticobulbar UMNs except for _ and _

A

Many cranial nerve motor nuclei receive bilateral corticobulbar UMNs except for lower facial nucleus and hypoglossal motor nucleus

102
Q

The [thalamic nucelus] receives sensory stimuli from the body (arms/legs/trunk)

A

The VPL receives sensory stimuli from the body (arms/legs/trunk)

103
Q

The [thalamic nucelus] receives sensory stimuli from the head/face

A

The VPM receives sensory stimuli from the head/face

104
Q

The _ pathways convey sensory stimuli from the head/face to the primary sensory cortex

A

The trigeminothalamic pathways convey sensory stimuli from the head/face to the primary sensory cortex

105
Q
A
106
Q

The trigeminothalamic tract involves [#] neurons

A

The trigeminothalamic tract involves 3 neurons

107
Q

Touch, pressure, and vibration from the face/head is carried by the first neuron of the trigeminothalamic tract and synapses at the [nucleus]

A

Touch, pressure, and vibration from the face/head is carried by the first neuron of the trigeminothalamic tract and synapses at the main/principle nucleus of the trigeminal

108
Q

The trigeminothalamic pathway decussates at the _

A

The trigeminothalamic pathway decussates at the pons
* The second neuron crosses over in the pons and ascends up the trigeminothalamic tract

109
Q

The second neuron of the trigeminothalamic tract travels up and synapses in the _

A

The second neuron of the trigeminothalamic tract travels up and synapses in the VPM of the thalamus

110
Q

The third neuron of the trigeminothalamic tract ascends through the internal capsule to the _

A

The third neuron of the trigeminothalamic tract ascends through the internal capsule to the primary sensory cortex

111
Q

Name (3) major classes of specialized sensory receptors found in our bodies

A
  1. Mechanical receptors
  2. Free nerve endings
  3. Proprioceptors
112
Q

Mechanical receptors are [structure] axons that are specialized to detect touch, pressure, vibration

A

Mechanical receptors are large encapsulated receptors with myelinated axons that are specialized to detect touch, pressure, vibration

113
Q

Are free nerve endings encapsulated?

A

No; free nerve endings are unencapsulated receptors and lightly myelinated

114
Q

Two types of free nerve endings:

A

Two types of free nerve endings:
Nociceptors for pain
Thermoceptors for temperature

115
Q

[Sensory receptors] detect mechanical stimuli from muscles/joints

A

Proprioceptors detect mechanical stimuli from muscles/joints

116
Q

(3) types of proprioceptors

A

(3) types of proprioceptors:
1. Muscle spindles (sense muscle length)
2. Golgi tendon organs (muscle tension)
3. Joint receptors (joint position)

117
Q

Meissner corpuscle senses _

A

Meissner corpuscle senses fine touch

118
Q

Pacinian corpuscle senses _

A

Pacinian corpuscle senses deep pressure, vibration

119
Q

Ruffini’s corpuscle senses _

A

Ruffini’s corpuscle senses stretch

120
Q

Merkel’s disks sense _

A

Merkel’s disks sense touch/pressure

121
Q

The mechanical receptors are all associated with [afferent axon type]

A

The mechanical receptors are all associated with AB axons
* These are large and myelinated
* Very quick

122
Q

Free nerve endings are associated with [afferent axon type]

A

Free nerve endings are associated with Adelta axons or C axons
* Adelta are small, lightly myelinated, slow while C axons are unmyelinated

123
Q

The proprioceptors are associated with [afferent axon type]

A

The proprioceptors are associated with Ia and II axons
* These are very large and myelinated
* Fastest action potentials

124
Q

Aalpha axons carry [information]

A

Aalpha axons carry proprioception

125
Q

Abeta axons carry [information]

A

Abeta axons carry touch, vibration

126
Q

Adelta axons carry [information]

A

Adelta axons carry pain, temperature
* These are fast and myelinated

127
Q

C axons carry [information]

A

C axons carry pain, temperature
* These are slow, unmyelinated

128
Q

_ is a group of diseases of myelin formation; has an intrinsic or genetic cause

A

Leukodystrophy is a group of diseases of myelin formation; has an intrinsic or genetic cause
* Contrast this with demyelinating diseases like MS

129
Q

Demyelinating diseases like MS typically involve myelin degeneration with relative preservation of _

A

Demyelinating diseases like MS typically involve myelin degeneration with relative preservation of axons
* Perivascular inflammatory cells (T lymphocytes) involved
* Loss of oligodendrocytes

130
Q

Burning pain is carried by _ sensory fibers

A

Burning pain is carried by C fibers
* Responsible for burning pain and hot temperatures
* Recall these are the slowest fibers because they are small and unmyelinated

131
Q

Sharp pain, gross touch, and cold temperature is carried by [sensory fibers]

A

Sharp pain, gross touch, and cold temperature is carried by Adelta fibers
* Recall that these are small and myelinated so faster than C fibers

132
Q

Proprioception, vibration, and fine touch is sensed by [sensory fibers]

A

Proprioception, vibration, and fine touch is sensed by A-alpha and A-beta fibers
* These are the fastest, they are large and myelinated