Intro to neuro Flashcards

1
Q

What plane?

A

Horizontal

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2
Q

What plane?

A

Coronal

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3
Q
A

Sagittal

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4
Q

Two hemispheres of the brain make up the _

A

Two hemispheres of the brain make up the cerebrum

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5
Q

The outer portion of the cerebrum is called the _

A

The outer portion of the cerebrum is called the cerebral cortex

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6
Q

The diencephalon is the space surrounding the _ and _

A

The diencephalon is the space surrounding the thalamus and hypothalamus

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7
Q

Name the portions of the brainstem superior to inferior

A

Midbrain
Pons
Medulla

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8
Q

The cerebrum is made up of the cerebral cortex and the _

A

The cerebrum is made up of the cerebral cortex and the underlying white and grey matter

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9
Q

ID structure

A

Longitudinal fissure

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10
Q

ID structure

A

Central sulcus

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11
Q

ID structure

A

Lateral (sylvian) fissure

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12
Q

ID structure

A

Parieto-occipital sulcus

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13
Q

ID structure

A

Corpus collosum

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14
Q

ID structure

A

Corpus collosum

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15
Q

_ cortices are the first regions to receive crude sensory information

A

Primary sensory cortices are the first regions to receive crude sensory information
* Sends information to association areas for detailed processing

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16
Q

_ is the last region in the cortex to receive motor information before it descends to lower regions

A

Primary motor cortex is the last region in the cortex to receive motor information before it descends to lower regions

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17
Q

(Primary sensory cortices/ association cortices) are responsible for detailed processing

A

Association cortices are responsible for detailed processing
* Constitutes the majority of the cortex

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18
Q

ID structure

A

Premotor cortex

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19
Q
A

Primary motor cortex

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20
Q

ID structure

A

Primary somatosensory cortex

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21
Q

ID structure

A

Broca area

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22
Q

ID structure

A

Wernicke area

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23
Q

The _ cortex is responsible for executive functions like planning and reasoning

A

The prefrontal cortex is responsible for executive functions like planning and reasoning

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24
Q

In addition to executive functions, the prefrontal cortex also has a role in _

A

In addition to executive functions, the prefrontal cortex also has a role in behavior, emotions, inhibition, learning, memory

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25
Q

The precentral gyrus is the site of the _

A

The precentral gyrus is the site of the primary motor cortex

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26
Q

The precentral gyrus is responsible for _

A

The precentral gyrus is responsible for execution of voluntary movements (primary motor cortex)

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27
Q

_ is responsible for language production

A

Broca’s area is responsible for language production

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28
Q

For most right handed individuals, broca’s area will be found in the (R/L) hemisphere

A

For most right handed individuals, broca’s area will be found in the left hemisphere

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29
Q

Damage to the _ lobe can result in hemispatial neglect

A

Damage to the parietal lobe can result in hemispatial neglect

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30
Q

The parietal lobe is responsible for _

A

The parietal lobe is responsible for sensation, perception, proprioception, balance, visuospatial processing, movement detection

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31
Q

The postcentral gyrus is the site for _

A

The postcentral gyrus is the site for primary somatosensory cortex

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32
Q

_ receives crude sensory information like touch, pressure, pain, temperature, proprioception

A

Primary somatosensory cortex receives crude sensory information like touch, pressure, pain, temperature, proprioception

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33
Q

The _ cortex helps with balance, equilibrium, spatial orientation, visual reflexes, and postural reflexes

A

The primary vestibular cortex helps with balance, equilibrium, spatial orientation, visual reflexes, and postural reflexes

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34
Q

The primary vestibular cortex is composed of several regions including the _ and _

A

The primary vestibular cortex is composed of several regions including the temporoparietal and frontal cortex

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35
Q

The primary motor and somatosensory cortices are organized somatotopically, with higher cortical surface area for areas with _

A

The primary motor and somatosensory cortices are organized somatotopically, with higher cortical surface area for areas with greater receptor innervation

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36
Q

The temporal lobe has functions in _

A

The temporal lobe has functions in audition, olfaction, emotion, memory
* Also routes visual information

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37
Q

Detection and localization of sound in the primary auditory cortex occurs _laterally

A

Detection and localization of sound in the primary auditory cortex occurs bilaterally

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38
Q

The _ is a hook-shaped structure in the innermost part of the temporal lobe that helps with olfactory processing

A

The uncus is a hook-shaped structure in the innermost part of the temporal lobe that helps with olfactory processing

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39
Q

The _ cortex and _ cortex are important structures for olfaction in addition to the uncus

A

The piriform cortex and entorhinal cortex are important structures for olfaction in addition to the uncus

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40
Q

The hippocampus and amygdala are located in the _ lobe

A

The hippocampus and amygdala are located in the temporal lobe

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41
Q

_ is the area responsible for language comprehension and it is located in the _

A

Wernicke’s area is the area responsible for language comprehension and it is located in the temporal lobe

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42
Q

Agrammatism and anomia are examples of _ aphasia

A

Agrammatism and anomia are examples of broca’s aphasia

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43
Q

_ aphasia is characterized by fluent but meaningless speech

A

Wernicke’s aphasia is characterized by fluent but meaningless speech

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44
Q

Broca’s area is linked to wernicke’s area by _

A

Broca’s area is linked to wernicke’s area by arcuate fasciculus

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45
Q

Cell bodies are found in (broca/ wernicke) while axons synapse in (broca/ wernicke)

A

Cell bodies are found in Wernicke’s area while axons synapse in Broca’s area

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46
Q

Motion recognition and orientation towards a visual stimulus is the responsibility of the _ lobe

A

Motion recognition and orientation towards a visual stimulus is the responsibility of the occipital lobe

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47
Q

The primary visual cortex is found along the _ sulcus

A

The primary visual cortex is found along the calcarine sulcus

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48
Q

The right visual field is processed in the (right/left) hemisphere

A

The right visual field is processed in the left hemisphere (contralateral)

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49
Q

The retinotopic organization of the occipital lobe means that higher cortical surface area means _

A

The retinotopic organization of the occipital lobe means that higher cortical surface area means higher receptor innervation and visual acuity

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50
Q

The _ region of the brain is important for balance, coordination, and fine muscle control

A

The cerebellum of the brain is important for balance, coordination, and fine muscle control

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51
Q

Broca’s area is found in the _ region

A

Broca’s area is found in the posterior inferior frontal gyrus

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52
Q

The primary auditory cortex is located in the _ region

A

The primary auditory cortex is located in the transverse temporal gyri (Heschl’s gyrus)

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53
Q

Wernicke’s area is located in the _ region

A

Wernicke’s area is located in the superior temporal gyrus

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54
Q

The primary olfactory cortex is found in the _ regions

A

The primary olfactory cortex is found in the uncus, piriform cortex, entorhinal cortex

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55
Q

The largest white matter tract in the brain is the _

A

The largest white matter tract in the brain is the corpus callosum

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56
Q

The purpose of the corpus collosum is to _

A

The purpose of the corpus collosum is to allow two hemispheres to communicate

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57
Q

ID the dark red structure

A

Lateral ventricles

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58
Q

ID the pink structures

A

Caudate nucleus

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59
Q

ID the yellow structures

A

Thalamus

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60
Q

ID the putamen

A
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61
Q

ID the globus pallidus interna and externa

A
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62
Q

ID the green structures

A

Subthalamic nucleus (superior)
Substantia nigra (inferior)

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63
Q

The substantia nigra is part of the [larger region] while the subthalamic nucleus is part of the [larger region]

A

The substantia nigra is part of the midbrain while the subthalamic nucleus is part of the diencephalon

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64
Q

_ matter is made up of bundles of axons

A

White matter is made up of bundles of axons

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65
Q

_ matter is made up of clusters of neuronal cell bodies

A

Grey matter is made up of clusters of neuronal cell bodies

66
Q

In the CNS a bundle of axons is called a _

A

In the CNS a bundle of axons is called a tract
* Or fasciculus, lemniscus, column, pathway

67
Q

In the PNS, a bundle of axons is called a _

A

In the PNS, a bundle of axons is called a nerve

68
Q

Grey matter is the brain is found in the outer region, _ and the inner region _

A

Grey matter is the brain is found in the outer region, cortex and the inner region nucleus

69
Q

Grey matter in the PNS is called _

A

Grey matter in the PNS is called ganglia
* Encapsulated aggregation of cell bodies found in the periphery
* We have spinal, cranial, autonomic ganglia

70
Q

_ fibers connect cortical areas

A

Association fibers connect cortical areas

71
Q

_ fibers connect the cortex to the brainstem and spinal cord

A

Projection fibers connect the cortex to the brainstem and spinal cord
* E.g. ascending sensory and descending motor tracts

72
Q

_ fibers connect similar areas between hemispheres

A

Commissural fibers connect similar areas between hemispheres

73
Q

The _ white matter tract connects the hemispheres and all four lobes

A

The corpus callosum connects the hemispheres and all four lobes

74
Q

The _ is the bidirectional tract that transmits information to and from the cerebral cortex/ brainstem

A

The internal capsule is the bidirectional tract that transmits information to and from the cerebral cortex/ brainstem

75
Q

Name the 3 parts of the internal capsule

A

Name the 3 parts of the internal capsule
1. Anterior limb
2. Genu
3. Posterior limb

76
Q

[Internal capsule segment] that helps in cognition, decision-making, emotion, and motivation

A

Anterior limb is the part of the internal capsule that helps in cognition, decision-making, emotion, and motivation

77
Q

[Internal capsule segment] helps with limb movement, bodily somatosensation, vision, audition

A

Posterior limb helps with limb movement, bodily somatosensation, vision, audition

78
Q

The “striatum” is made up of the _ + _

A

The “striatum” is made of the caudate nucleus + putamen

79
Q

The lentiform nucleus is made up of the _ + _

A

The lentiform nucleus is made up of the putamen + globus pallidus

80
Q

The function of the basal ganglia (collection of structures) is to _

A

The function of the basal ganglia (collection of structures) is to modulate voluntary movement and posture

81
Q

Name the four divisions of the diencephalon

A

Name the four divisions of the diencephalon:
1. Epithalamus
2. Thalamus
3. Hypothalamus
4. Subthalamus

82
Q

The epithalamus contains the [structure]

A

The epithalamus contains the pineal gland
* Melatonin –> circadian rhythm

83
Q

The _ is a central hub in the brain that processes and transmits sensory and motor information

A

The thalamus is a central hub in the brain that processes and transmits sensory and motor information

84
Q

The _ has autonomic, endocrine, and limbic functions and has a role in motivated behaviors

A

The hypothalamus has autonomic, endocrine, and limbic functions and has a role in motivated behaviors

85
Q

The subthalamus contains the subthalamic nucleus which is part of the _ and functions to _

A

The subthalamus contains the subthalamic nucleus which is part of the basal ganglia and functions to modulate motor control

86
Q

ID the structure

A

Epithalamus (pineal gland)

87
Q

ID the structure

A

Thalamus

88
Q

ID the structure

A

Hypothalamus

89
Q

The ventral anterior nucleus (VA) has _ functions

A

The ventral anterior nucleus (VA) has motor functions

90
Q

The VA gets input from _ and sends output to _

A

The VA gets input from globus pallidus and sends output to premotor cortex

91
Q

Ventral lateral nucleus (VL) has _ functions

A

Ventral lateral nucleus (VL) has motor functions

92
Q

The VL gets input from the _ and sends output to the _

A

The VL gets input from the cerebellum & basal ganglia and sends output to the primary motor cortex

93
Q

The _ and _ thalamic nuclei coordinate motor function

A

The VA and VL thalamic nuclei coordinate motor function
* Vacate from ants
* Vodka ~walk~ laterally

94
Q

The _ thalamic nucleus relays information about bodily sensation

A

The ventral posterolateral (VPL) nucleus relays information about bodily sensation
* Vibration, pain, pressure, proprioception, light touch = V. P. L.

95
Q

The ventral posteromedial nucleus (VPM) is responsible for relaying _

A

The ventral posteromedial nucleus (VPM) is responsible for relaying facial sensation & taste
* Vocalist post malone has distasteful facial tattoos

96
Q

The VPL gets input from _ and _

A

The VPL gets input from spinothalamic and dorsal column medial lemniscus pathways

97
Q

The VPL sends output to the _

A

The VPL sends output to the primary somatosensory cortex

98
Q

The ventral posteromedial nucleus gets input from _ and _

A

The ventral posteromedial nucleus gets input from trigeminal nerve and gustatory pathway

99
Q

The VPM sends output to the _

A

The VPM sends output to the primary somatosensory cortex

100
Q

The _ thalamic nucleus relays vision information

A

The lateral geniculate nucleus (LGN) thalamic nucleus relays vision information
* Long gone the night

101
Q

The lateral geniculate nucleus gets input from the _ areas

A

The lateral geniculate nucleus gets input from the:
* Optic nerve (CN II)
* Optic chiasm
* Optic tract

102
Q

The LGN sends output to the _

A

The LGN sends output to the primary visual cortex

103
Q

The _ thalamic nucleus relays hearing info

A

The medial geniculate nucleus (MGN) thalamic nucleus relays hearing info

104
Q

The MGN receives input from the _

A

The MGN receives input from the superior olive & inferior colliculus of the tectum

105
Q

The MGN sends output to the _

A

The MGN sends output to the primary auditory cortex

106
Q

The _ and _ thalamic nuclei send output to the primary somatosensory cortex

A

The VPL and VPM thalamic nuclei send output to the primary somatosensory cortex

107
Q

The lateral nucleus (hypothalamus) stimulates _

A

The lateral nucleus (hypothalamus) stimulates hunger

108
Q

The ventromedial nucleus (hypothalamus) stimulates _

A

The ventromedial nucleus (hypothalamus) stimulates satiety

109
Q

The lateral nucleus activity is stimulated by [hormone] and inhibited by [hormone]

A

The lateral nucleus activity is stimulated by ghrelin and inhibited by leptin

110
Q

The ventromedial nucleus is stimulated by [hormone]

A

The ventromedial nucleus is stimulated by leptin

111
Q

A lesion of the _ hypothalamic nucleus can cause anorexia or failure to thrive

A

A lesion of the lateral nucleus can cause anorexia or failure to thrive

112
Q

A lesion of the _ hypothalamic nucleus can cause hyperphagia

A

A lesion of the ventromedial nucleus can cause hyperphagia

113
Q

The anterior nucleus (hypothalamus) is responsible for _

A

The anterior nucleus (hypothalamus) is responsible for cooling & parasympathetic ANS

114
Q

The posterior nucleus (hypothalamus) is responsible for _

A

The posterior nucleus (hypothalamus) is responsible for heating & sympathetic nucleus

115
Q

A lesion of the [hypothalamic nucleus] can cause hyperthermia

A

A lesion of the anterior nucleus can cause hyperthermia

116
Q

A lesion of the [hypothalamic nucleus] can cause hypothermia

A

A lesion of the posterior nucleus can cause hypothermia

117
Q

The suprachiasmatic nucleus (hypothalamus) is responsible for _

A

The suprachiasmatic nucleus (hypothalamus) is responsible for circadian rhythms
* SCN = sun sensing

118
Q

The paraventricular nucleus (hypothalamus) synthesizes and releases _

A

The paraventricular nucleus (hypothalamus) synthesizes and releases oxytocin
* SAD POX

119
Q

The supraoptic nucleus (hypothalamus) synthesizes and releases _

A

The supraoptic nucleus (hypothalamus) synthesizes and releases ADH
* SAD POX

120
Q

The preoptic nucleus (hypothalamus) is responsible for _ and _

A

The preoptic nucleus (hypothalamus) is responsible for thermoregulation and sexual behaviors

121
Q

A lesion of the preoptic nucleus can result in _ syndrome

A

A lesion of the preoptic nucleus can result in Kallmann syndrome
* Underdeveloped or absent secondary sex characteristics + impaired sense of smell

122
Q

Hyposmia or anosmia may be caused by a lesion at the [hypothalamic nucleus]

A

Hyposmia or anosmia may be caused by a lesion at the preoptic nucleus

123
Q

The [hypothalamic nucleus] is responsible for producing and releasing gonadotropin-releasing hormone (GnRH)

A

The preoptic nucleus is responsible for producing and releasing gonadotropin-releasing hormone (GnRH)

124
Q

The function of the limbic system can be remembered with the mnemonic _

A

The function of the limbic system can be remembered with the mnemonic “the 5 F’s”
1. Feeding
2. Fleeing
3. Fighting
4. Feeling
5. Sex

Regulates long term memory, emotion, behavioral regulation, autonomic responses, endocrine responses, olfaction, pain affect

125
Q

The _ and _ brain structures are important for storage and retrieval of procedural memories

A

The basal ganglia and cerebellum brain structures are important for storage and retrieval of procedural memories
* E.g remembering how to ride a bike

126
Q

The _ is involved in emotion memory, a form of implicit memory

A

The amygdala is involved in emotional memory, a form of implicit memory

127
Q

The _ and _ regions of the brain are involved in short and long term memory

A

The hippocampus and cortex regions of the brain are involved in short and long term memory

128
Q

Semantic and episodic are two forms of _ memory

A

Semantic and episodic are two forms of declarative (explicit) memory

129
Q

Name 3 main regions of the limbic system

A

Name 3 main regions of the limbic system
1. Cerebral cortex
2. Diencephalon
3. Reticular formation

130
Q

Name the components of the cerebral cortex (part of limbic system)

A

Name the components of the cerebral cortex (part of limbic system)
1. Cingulate gyrus
2. Parahippocampal gyrus
3. Dentate gyrus
4. Fornix
5. Amygdala
6. Hippocampus

131
Q

The _ connects the limbic structures to the prefrontal cortex

A

The cingulate gyrus connects the limbic structures to the prefrontal cortex

132
Q

The _ is involved in enthusiasm, passion, pain unpleasantness, and avoidance; so a lesion here can result in flattened affect

A

The cingulate gyrus is involved in enthusiasm, passion, pain unpleasantness, and avoidance; so a lesion here can result in flattened affect

133
Q

The parahippocampal gyrus, amygdala, and hippocampus are all components of the _ lobe

A

The parahippocampal gyrus, amygdala, and hippocampus are all components of the temporal lobe

134
Q

The parahippocampal gyrus has functions in _

A

The parahippocampal gyrus has functions in episodic memory
* E.g. specific details about events, time, and places
* Helps with navigational memory

135
Q

A lesion in the [brain region] may result in loss of empathy and remorse, new-onset anxiety and aggression

A

A lesion in the amygdala may result in loss of empathy and remorse, new-onset anxiety and aggression

136
Q

Bilateral damage of the amygdala can cause _ syndrome

A

Bilateral damage of the amygdala can cause Kluver-Bucy syndrome

137
Q

_ is a limbic system region that is particularly epileptogenic (seizures tend to originate here)

A

Hippocampus is a limbic system region that is particularly epileptogenic (seizures tend to originate here)

138
Q

A lesion in the hippocampus can result in _

A

A lesion in the hippocampus can result in memory loss, anterograde amnesia
* Hippocampus has a big role in learning and memory
* E.g. Alzheimer’s disease

139
Q

ID the structure

A

Mamillary bodies

140
Q

Bilateral damage to the mamillary bodies may result in _ syndrome

A

Bilateral damage to the mamillary bodies may result in Korsakoff’s syndrome

141
Q

Korsakoff syndrome is a chronic memory disorder that most often causes (anterograde/retrograde) amnesia

A

Korsakoff syndrome is a chronic memory disorder that most often causes anterograde amnesia
* Can’t form new memories

142
Q

Chronic alcohol users are at risk for [vitamin deficiency] which can lead to anterograde amnesia & confabulation (Korsakoff’s syndrome)

A

Chronic alcohol users are at risk for vitamin B1 (thiamine) deficiency which can lead to anterograde amnesia & confabulation (Korsakoff’s syndrome)

143
Q

The mesolimbic pathway (part of the limbic system) originates at the _ and targets the _

A

The mesolimbic pathway (part of the limbic system) originates at the ventral tegmental area (VTA) and targets the nucleus accumbens
* It also projects to the amygdala and frontal cortex

144
Q

The mesolimbic pathway is involved in _

A

The mesolimbic pathway is involved in pleasure, reward, reinforcement, addiction

145
Q

_ is located in the midbrain and contains dopaminergic neurons which produce dopamine

A

Ventral tegmental area (VTA) is located in the midbrain and contains dopaminergic neurons which produce dopamine

146
Q

Anterior nuclei of the thalamus are part of the limbic system and have a role in _

A

Anterior nuclei of the thalamus are part of the limbic system and have a role in learning & memory
* Part of the papez circuit

147
Q

The _ is a cluster of nuclei in the brainstem that controls arousal, alertness, breathing, etc

A

The reticular formation is a cluster of nuclei in the brainstem that controls arousal, alertness, breathing, etc
* Also home to nuclei that make NT like serotonin, NE

148
Q

The _ is a circuit for memory and emotions that includes the hippocampus, fornix, mammillary bodies, anterior thalamic nuclei, cingulate gyrus, and entorhinal cortex

A

The Papez circuit is a circuit for memory and emotions that includes the hippocampus, fornix, mammillary bodies, anterior thalamic nuclei, cingulate gyrus, and entorhinal cortex

149
Q

The hippocampus communicates with the mammillary bodies via the _ (Papez circuit)

A

The hippocampus communicates with the mammillary bodies via the fornix (Papez circuit)

150
Q

The mamillary bodies communicate with the anterior thalamic nuclei via the _ tract (Papez circuit)

A

The mamillary bodies communicate with the anterior thalamic nuclei via the mammillothalamic tract (Papez circuit)

151
Q

The anterior thalamic nuclei communicate with the cingulate cortex via the _

A

The anterior thalamic nuclei communicate with the cingulate cortex via the internal capsule

152
Q

The cingulate cortex communicates with the hippocampus via the _

A

The cingulate cortex communicates with the hippocampus via the cingulum

153
Q

Papez circuit:
Hypothalamus –> _ –> _ –> _ –> hypothalamus

A

Papez circuit:
Hypothalamus –> mammillary bodies –> anterior thalamic nuclei –> cingulate cortex –> hypothalamus

154
Q

What would happen if the temporal lobes were removed or damaged?

A
  • Would spare intelligence + procedural memory
  • Would impair declarative memory + anterograde memory
  • Think of patient H.M
155
Q

Damage to the medial temporal lobes may result in _ syndrome, characterized by behaviors such as _

A

Damage to the medial temporal lobes may result in Kluver-Bucy syndrome, characterized by behaviors such as hyperorality, hypersexuality, emotional blunting, memory impairments (etc)

156
Q

A common infectious cause of kluver-bucy syndrome is _

A

A common infectious cause of kluver-bucy syndrome is HSV-1
* Recall that HSV-1 causes temporal lobe encephalitis

157
Q

The mesolimbic pathway (reward pathway) is stimulated by things like _

A

The mesolimbic pathway (reward pathway) is stimulated by things like food, drink, sex, ethanol, cocaine, amphetaminesm opiates, nicotine
* Over time the nucleus accumbens can become desensitized

158
Q
A

Thalamus

159
Q
A

Thalamus

160
Q
A