White Blood Cells Flashcards
Monopoiesis
Monoblast
Promonocyte
Monocyte
Lymphopoiesis
Lymphoblast
Prolymphoblast
Lymphocyte
Granulopoiesis
Myeloblast Promyelocyte Myelocyte Metamyelocyte Band Segmented Neutrophil/Eosinophil/Basophil
Thrombopoiesis
Megakaryoblast
Promegakaryocyte
Megakaryocyte
Platelet
Signs of an Immature Cell
Primary granules
Visible nucleoli
Non segmented nucleus
Prince-Nez Cell
Two lobes of the neutrophils nucleus are round and joined by a fine strand
Seen in Pelger-Huet anomaly
Stodmeister Cell
Non/monolobed neutrophil nucleus
Seen in Pelger-Huet anomaly
L1, L2, L3 Lymphocytes
L1: very small lymphocytes with almost no cytoplasm
L2: bigger lymphocytes with varying sizes, irregular clefting, nucleoli, and chromatin
L3: even bigger lymphocytes with vacuoles
Atypical Lymphs
Reactive: larger, more cytoplasm, irregular shape
CLL: soccer ball/turtle cells
Hairy Cell
Seen in HCL
Cleft Lymphocyte
Butt cells
Associated with Bordetella pertussis/Whooping cough
Plasma Cell
Activated B cells that produce large quantities of antibody
Usually mono-lobed and only in bone marrow
Plasmacytoid Lymphocyte
Cross between lymph and plasma cell
Flaming Plasma Cell
Associated with IgA production
Dutcher Bodies
Immunoglobulin Crystals
Thin clear rods in lymphocytes
Seen in mature B cell leukemias (CLL, multiple myeloma)
Dohle Bodies
RNA associated with rough ER in neutrophils
Toxic Granulation
Production of secondary granules has not caught up with cell maturity
Seen as large, dark granules and vacuoles in neutrophils
Vacuolization
Holes in the cytoplasm of the cell
Auer Rods
Thin pink/purple rods in immature granulocyte cytoplasm
Formed by the fusion of primary granules
Hyper/Hyposegmentation
Lots of segments
Not a lot of segments
