Phagocytosis

Question 1

Oxidative Burst

Answer 1

AKA Respiratory burst
2O2 + NADPH –(NADPH oxidase)–> 2O2 + NADP(+) + H(+)
2O2(-) + 2H(+) –(superoxide dismutase/spont)–> H2O2 + O2

Hydrogen peroxide isn’t very good at killing stuff

Question 2

Myeloperoxidase

Answer 2

Dependent
H2O2 + Cl(-) –(myeloperoxidase)–> OCl(-) + H2O

Independent
H2O2 –(spont)–> OH(-) + OH(-)

Bleach is better at killing stuff

Question 3

Steps of Phagocytosis

Answer 3

Chemotaxis/Diapedesis
Opsonization
Ingestion
Degranulation