White Blood Cell Pathology: Approach to Lymphadenopathy Flashcards
non tender lymphnodes are an indication of
malignancy: can be stage 1-II lymphomas (hodgkins, non-hodgkins etc) or metastatic cancer.
age distribution between non-hodgkin and hodgkin lymphoma
characteristic cell of classical hodgkin lymphoma
reed-sternberg cells and vairants.
surrounded by eosinophils, neutrophils, lymphocytes and plasma cells.
obvious reed-sternberg cells makes this most likely a CHL (classic HODGKIN LYMPHOMA)
a large amount of cells are stained with the CD15 marker, indicating that there are an abnormal amount of CD15 cells present– these are reed sternberg cells.
CD15 and CD30 are stains for reed sternberg cells and thus are indicating a CHL.
( CD30 and CD15 are also expressed on Reed-Sternberg cells typical for Hodgkin’s lymphoma ( and anaplastic T cell lymphoma)
follicular lymphoma. way too many follicles, causing a B cell lymphoma. most common B cell lymphoma in adults
non hodgkins.
usually has an indolent clinical course ecept in high grade cases. treated wiht a single reafent and relapse and progression to affressive disease iss common.
this cell has a stain for the CD20 marker, indicating that its staining for B cells. this could thus indicate CLL or B cell folliclular nonhodgkin lympoma.
the. lack of staining on CD3 indicates that this is not a T cell lymphoma
these slides show:
diffuse large B cell lymphoma
T/F if you suspect a lymphoma you should do a fine needle aspirate
false.
T/F diffuse large B cell lymphoma is indolent
false. it’s aggressive but curable. most of the indolent ones are not.
