CPC: Biliary and Pancreatic Neoplasia Flashcards
which gender is affectd more by gallbladder cancer
females.
risk factors to cholangiocarcinoma (gall bladder cancer)
3 “regions” of cholangiocarcioma
intrahepatic, perihiliar, and distal.
TF: intra-hepatic Cholangiocarcinoma will present with severe biliary colic. What other symptoms present intra-hepatic CCA?
false. it’s usually asymptomatic and detected on physical exam.
- not jaundiced usually
- just general fatigue, malaise, anorexia, weightloss, adominal pain
- increased ALP an GGT
T/F Hilar or extrahepatic CCA presents with jaundice. What other constitiutional symptoms are presen?
true. Unlike inta-hepatic CCA, hilar cca often presents with painless jaundice (similar to pancreatic cancer)
- cholangitis is uncommon.
- pruritis (could be blocking bile duct)
- malaise, anorexia, weight loss
- abdominal pain
- palpable abdominal mass
- conjugated bilirubin high
- ALP and GGT >>> ALT and ASt.
T/F Hilar CCA will present with higher levels of indirect bilirubin
false. it is “after” the liver, so it actually will have elevated ALP GGT and CONJUGATED bilirubin
T/F Gall Bladder CA in the gall bladder presents with biliary colic
true. but it tends to be more constant.
Someone presents with painless jaundice, pruritis, and abdominal epigastric pain that radiates to the back. they’ve lost weight in the last few months and are tired all the time.
ddx?
probably pancreatitis more so because of the radiating back pain.
T/F lipase is elevated in PDA (pancreatic ductal neoplasia/adenocarcinoma)
False. there may be elevated liver enzymes, conjugated bilirubin. BUT lipase/amylase usually normal.
cancer in which part of the pancreas presents earlier?
head of pancreas: painless jaundice, clay stool, change in bowel habits/constipation. presents earlier
body of pancreas: pain radiating in the back, epigastric pain, going to the back. Non resectable.
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