WHENT SCREEN LIPOPROTIEN A

Question 1

What is Lipoprotein (a) associated with?

Answer 1

Very high cardiovascular disease risk and aortic stenosis

Lipoprotein (a) is considered highly atherogenic.

Question 2

How is Lipoprotein (a) predominantly inherited?

Answer 2

Genetically inherited

This means that levels of Lipoprotein (a) are largely determined by genetics.

Question 3

What is the odds ratio for cardiovascular risk associated with high levels of Lipoprotein (a)?

Answer 3

1.7 (95% CI, 1.4-1.9)

This indicates a significant increase in cardiovascular risk for individuals in the upper tertile of Lipoprotein (a) levels.

Question 4

What does a high level of Lipoprotein (a) indicate regarding treatment?

Answer 4

Need for aggressive lipid-lowering therapy

High levels suggest that standard lipid-lowering treatments may not be sufficient.

Question 5

What is currently being developed in relation to Lipoprotein (a)?

Answer 5

New therapies

These therapies are still in development and require longer trials to assess their effectiveness.

Question 6

Who should be screened for Lipoprotein (a)?

Answer 6

Those at very high cardiovascular risk, with premature cardiovascular disease, known elevated lipoprotein (a), or progressive disease despite LDL-lowering

Screening is particularly important for individuals with a history or risk factors for cardiovascular issues.