NAFLD SCREENING Flashcards
PIC
What are high-risk groups for NAFLD?
High-risk groups for NAFLD include prediabetes, type 2 diabetes (T2D), obesity, and/or 22 cardiometabolic risk factors.
What is the FIB-4 index for low risk?
FIB-4 index is <1.3 for low risk.
What is the FIB-4 index for high risk?
FIB-4 index is >2.67 for high risk.
What is the FIB-4 index for indeterminate risk?
FIB-4 index is between 1.3 - 2.67 for indeterminate risk.
What tests are ordered for indeterminate risk?
Order a second test: Liver Stiffness Measurement (LSM) by elastography or ELF blood test.
What are the criteria for low risk in fibrosis risk stratification?
Low risk is defined as FIB-4 <1.3 or LSM <8 kPa or ELF <7.7.
What are the criteria for indeterminate risk in fibrosis risk stratification?
Indeterminate risk is defined as FIB-4 1.3 - 2.67 or LSM 8 - 12 kPa or ELF 7.7 - 9.8.
What factors increase cirrhosis risk?
Cirrhosis risk is higher with T2D (or prediabetes), age >50, higher BMI (40 kg/m²), more metabolic risk factors, and genetic factors (i.e., PNLPAS).
What are the criteria for high risk in fibrosis risk stratification?
High risk is defined as FIB-4 >2.67 or LSM >12 kPa or ELF >9.8.
Who manages high-risk patients?
Managed by primary care team, endocrinologist, and others.
What should be the focus of care for high-risk patients?
Focus care on obesity management and cardiovascular disease (CVD) prevention.
When should a referral to a liver specialist be made?
Referral to a liver specialist is needed for additional proprietary biomarkers or imaging (MRE, cT1, other).
What is the role of a multidisciplinary team in cirrhosis prevention?
A multidisciplinary team is essential to prevent cirrhosis and CVD.
What does FIB-4 stand for?
FIB-4 = Fibrosis-4 index.
