KPD Flashcards
What is Ketosis-prone diabetes formerly known as?
Flatbush or type 1b diabetes
What percentage of newly diagnosed patients with Ketosis-prone diabetes in the U.S. are Black or Hispanic?
20% to 50%
What condition do patients with Ketosis-prone diabetes often present with?
Diabetic ketoacidosis
Why is predicting insulin therapy duration in Ketosis-prone diabetes challenging?
Due to variable patient responses and disease progression
What are the two main focuses of the classification systems developed for Ketosis-prone diabetes?
- Beta-cell autoimmunity
- Beta-cell function
How is beta-cell autoimmunity measured?
By glutamic acid decarboxylase and insulinoma-associated protein 2 antibodies
How is beta-cell function assessed?
By C-peptide concentration
Which classification system is the most accurate for predicting the need for insulin treatment?
The Aß system
What is the sensitivity and specificity of the Aß system for predicting insulin treatment needs 12 months post-diabetic ketoacidosis?
- Sensitivity: 99%
- Specificity: 96%
