Wernicke and Korsakoff Flashcards
1
Q
What is the pathology in Wernicke and Korsakoff?
A
Thiamine deficiency
2
Q
What causes Wernicke?
A
Usually alcoholism
Others- stomach cancer, persistent vomiting, dietary deficiency
3
Q
What are the features of Wernicke?
A
Nystagmus Opthalmoplegia Ataxia Confusion, altered GCS Peripheral sensory neuropathy
4
Q
What investigations are done for Wernicke?
A
Bloods
MRI
5
Q
What is the management of Wernicke?
A
Urgent replacement of thiamine
Pabrinex
6
Q
What is the complication of Wernicke?
A
Progression to Wernicke Korsakoff
7
Q
What causes Korsakoff?
A
Usually alcoholism
Other- malnutrition, persistent vomiting
8
Q
What are the features of Korsakoff?
A
Anterograde amnesia
Retrograde amnesia
Confabulation
9
Q
What is the management of Korsakoff?
A
Urgent replacement of thiamine
Pabrinex
10
Q
What is Wernicke-Korsakoff?
A
Acute Wernicke encephalopathy phase followed by chronic Korsakoff syndrome
