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Neuro AM > Myaesthenia gravis > Flashcards

Myaesthenia gravis Flashcards

1
Q

What is MG?

A

Autoimmune condition with antibodies against nicotinic acetylcholine receptors at NMJ

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2
Q

Who is MG mainly seen in?

A

Females <40

Males >60

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3
Q

What is MG associated wth?

A

Other autoimmune onditions
Thymoma in 15%
Thymis hyperplasia in 60%!

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4
Q

What is the presentation of MG?

A

Fatigable weakness
Early= generally eye weakness, double vision, ptosis
Becomes more severe and generalised- dysphagia, slow slurred speech etc

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5
Q

What investigations are done for MG?

A

AChR antibody
AntiMusk antibody
Single fibre EMG- fatigue
CT chest- look for thymoma

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6
Q

What is the 1st line management of MG?

A

Acetylcholinesterase inhibitors- e.g. pyridostigmine

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7
Q

What is the 2nd line management of MG?

A

Immunosuppression
IVIg
Thymectomy

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8
Q

What is the management of a myasthenia crisis?

A

Intubation/NIV
IVIg
Plasmapheresis

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9
Q

What is important to remember when treating patients with MG?

A 
Lots of drugs to avoid
BB
Gentamycin, erythromycin, azithromycin
Ciprofloxacin
Lithium
Opiates
More
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Neuro AM (21 decks)

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