Lambert Eaton syndrome Flashcards

1
Q

What is Lambert Eaton?

A

Autoimmune or paraneoplastic condition creating antibodies against voltage gated calcium channels at the NMJ

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2
Q

What is Lambert Eaton associated with?

A

Main= lung cancer
Less= breast and ovarian cancer
Other autoimmune conditions

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3
Q

What is the presentation of Lambert Eaton?

A

Limb girdle weakness, esp in legs
Weakness gets better with repeated contraction
Hyporeflexia

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4
Q

hat investigations are done for Lambert Eaton?

A

EMG
Bloods- antibodies
CT chest

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