Lambert Eaton syndrome Flashcards
1
Q
What is Lambert Eaton?
A
Autoimmune or paraneoplastic condition creating antibodies against voltage gated calcium channels at the NMJ
2
Q
What is Lambert Eaton associated with?
A
Main= lung cancer
Less= breast and ovarian cancer
Other autoimmune conditions
3
Q
What is the presentation of Lambert Eaton?
A
Limb girdle weakness, esp in legs
Weakness gets better with repeated contraction
Hyporeflexia
4
Q
hat investigations are done for Lambert Eaton?
A
EMG
Bloods- antibodies
CT chest