Neuroleptic malignant syndrome Flashcards
1
Q
What is neuroleptic malignant syndrome?
A
Life threatening reaction to neuroleptic/antipsychotic medication
2
Q
What drugs is neuroleptic malignant syndrome most associated with?
A
Haloperidol
Chlorpromazine
3
Q
What drugs is neuroleptic malignant syndrome less associated with?
A
Clozapine Olanzapine Risiperidone Quetiapine Levodopa
4
Q
What are the features of neuroleptic malignant syndrome?
A
High fever Confusion, altered conciousness Muscle rigidity Sweating Autonomic imbalance Tachycardia
5
Q
What investigations ar done for neuroleptic malignant syndrome?
A
Bloods- elevated WBC and CK
CT/MRI to rule out other causes
6
Q
What is the management of neuroleptic maligantn syndrome?
A
Medical emergency!
Bromocriptine- dopamine agonist
Stop drug, cool and support
7
Q
What are the complications of neuroleptic malignant syndrome?
A
Rhabdomyelosis
Renal failure
