Week 9 Ch. 47 Flashcards
Sensory receptors, neuronal circuits for processing information
Mechanoreceptor stimuli
mechanical compression/ stretching
Thermoreceptor stimuli
Temperature
*specific neurons dedicated to hot or cold
Nociceptor stimuli
Physical or chemical damage (pain)
Electromagnetic receptor stimuli
Light on retina of eye
Chemoreceptor stimuli (5 examples)
- taste
- smell
- oxygen level in arterial blood
- Osmolality of body fluids
- CO2 concentration
Each receptor is sensitive to ____ stimuli
1 type of stimuli
Labeled line principle
Specificity of nerve fibers transmitting one modality of sensation
Each nerve tract terminates at a specific point in nervous sytem
When a stimuli excites a receptor the effect is:
to change the membrane electrical potential (allows action potential)
Four way to excite receptors (and open ion channels)
- Mechanical deformation of receptor
- Application of Chemical to membrane (ligand gated)
3.Change in temp (alters permeability) - Electromagnetic (light changes receptor membrane)
Max amplitude of receptor potentials
100 mV (-70 to +30)
Pacinian corpuscle facilitiates
compression response
Pancinian corpuscle MOA
compression anywhere on capsule layers will elongate, deform, or indent central fiber
Deformation of pancinian copuscle causes
Sodium channels to open –> action potential at nodes of ranvier
Strength of stimuli in pacinian corpuscle and reasoning
rapid increase in amplitude, then decrease in amplitude as stimulus strength increases
allows receptor to be very sensitive to weak stimuli but only max out with max stimuli
Receptor adaptation
all sensory receptors adapt partially or completely to constant stimulus
Pain receptors may never fully adapt
Pacinian corpuscle adaptation
Fluid is redistributed to receptor potential is no longer disturbed
(Coin lab)
Rapidly adapting receptors (3)
- free nerve endings
- Muscle spindle
- Tactile hair
*aka rate, movement or phasic receptors
Rapidly adapting receptors only react when
stimulus strength changes
Tonic receptors role
keep brain informed of the bodies relationship in space at all times
Tonic receptor examples (4)
- Baroreceptors
- Pain receptors
- Macula receptors
- Chemoreceptors
What affects speed of signal transmission
Myelinated = faster
Larger diameter = faster
Type A fibers
(characteristics and subdivisions)
-myelinated
-Subdivided into alpha, beta, gamma delta
Type C fibers
(characteristics and location)
-Small, unmyelinated (low velocity)
-1/2 sensory fibers in peripheral and postganglionic autonomic
Spatial summation
increasing signal strength d/t increasing NUMBER of nerve fibers
Temporal summation
increasing signal strength d/t increasing FREQUENCY of nerve impulses on each fiber
AP after AP after AP after AP = brain knows a lot is going on
Neuronal Pools
spacial division of neurons dedicated to similar function
Facilitating of neurons
moves toward + but not causing AP
Neurons reaching threshold =
firing
Facilitated zone has (proportion of axon terminals)
fewer axon terminals
Discharge zone has (proportion of axon terminals)
many more axon terminals/synapses (easier to reach AP)
Divergence of neurons - how do them amplify?
- Amplifies: signal spreads to increasing number of neursons
- Mulitple tracts: signal transmitted in different directions - spread the message
Divergence of neurons - multiple tracts
Signal transmitted in different directions - spread the message
How does Divergence excite nerve fibers (2)?
- Amplifies signal
- Signal transmitted through multiple tracts
Convergence (2)
- signals from multiple neurons to the same neuron
- Input to single neuron from multiple others
Reciprocal Inhibition Circuit
Outward signals can be excitatory in one direction and inhibitory in another direction
Example of reciprocal inhibition circuit
Walking: excites muscles on front of leg, inhibits muscles on back of leg
Afterdischarge
long acting synaptic transmitters involved continue to fire so long as potential lasts
prolonged output
Reverberatory and example
positive feedback within neuronal circuit to re-excite
ex. respiratory centers of medulla and pons never fatigue enough to stop
Intrinsic neuronal excitability and examples
membrane potentials rise above threshold. “Carrier wave system”
don’t cause signal, but control level of intensity
ex. tone, iris, HR
Inhibitory circuits
Keep things ‘off’ unless there is enough to turn it on
Synaptic fatigue occurs when _____ and causes_____
occurs with prolonged excitation, causes transmission to become weaker
Short term overuse of synapse causes
decreased sensitivity
short term underuse of synapse causes
increased sensitivity
Long term synaptic fatigue causes
change in the number of receptor proteins