Week 1 cells basic Flashcards

1
Q

Physiology

A

Characteristics and mechanisms that make a living being

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2
Q

Cells and function

A

Specialized, adapt to perform on or a few functions

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3
Q

Oxygen and cell fucntion

A

oxygen reacts with carbs, fats and proteins to release energy

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4
Q

extracellular fluid definition and characteristics

A

Outside of cell “internal environment”
-in constant motion
-Circulating blood and capillary walls (exchange of O2 and waste)

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5
Q

Homeostasis

A

Ions, nutrients and waste products maintained within a small range

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6
Q

Compensatory mechanisms

A

Try to maintain homeostasis, make it difficult to determine PRIMARY cause of disease

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7
Q

Pathophysiology

A

explain physiological processes altered in disease or injury

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8
Q

Extracellular fluid transport stage 2

A

Movement between blood capillaries and intercellular spaces of tissue cells

Follows concentration gradients

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9
Q

Capillary walls are permeable to

A

most molecules, NOT plasma

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10
Q

Plasma protiens

A

Do not go into intercellular spaces (cant cross capillary walls)

i.e. albumin, fibrinogen, globulins

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11
Q

Distance form cells to capillary

A

max 2 cells away (50uM)

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12
Q

Tiem to complete circulatory circuit

A

1 min

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13
Q

Respiratory origin nutrients

A

O2 via alveolar membrane

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14
Q

GI tract nutrient origin

A

Carbs, fatty and amino acids (small intestine = absorbtion)

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15
Q

Liver origin nutrients

A

alters substances to useable forms, filters out waste and sends back nutrients

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16
Q

Musculoskeletal origin nutrients

A

obtain food

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17
Q

Respiratory waste/end product

A

CO2

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18
Q

Kidney waste removal

A

Urea and uric acid (broken down amines)

Screens fluids, reabsorbs 99%

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19
Q

GI tract waste products

A

undigested material

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20
Q

Liver waste/end prodcuts

A

bile

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21
Q

Systems that play a role in regulation

A

Nervous, endocrine
(nervous fast, endocrine slow)

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22
Q

Nervous system basic route

A

sensory input–>central nervous (decision)–>motor output

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23
Q

Nervous system regulation system

A

Autonomic nervous system (SNS, PNS)

24
Q

Endocrine system regulation route

A

hormones travel via blood to target

25
Protection system
Immune system (distinguish and destruct)
26
O2 and CO2 in extracellular fluid (control system)
HbB is oxygen buffering Reespiratory center - change breathing rate
27
Control system in arterial blood pressure
1. Pressure acts on baroreceptors 2. baroreceptors signal to vasomotor center of medulla 3. Error signal sent to SNS 4. Appropriate effectors trigger change in. blood vessels and heart
28
Negative feedback
most systems Result is opposite of initiating stimulus
29
Gain of a control system =
Correction/Error Correction = points corrected by body to reestablish homeostasis error = the difference between starting point to end point
30
Positive feedback
Vicious cycle, can lead to instability ex. Blood clotting, childbirth, nerve signals, lactation/letdown
31
Protoplasm
substances that make up a cell -water -ions -proteins -lipids -carbs
32
% water in cell
70%-85%
33
Role of ions in protoplasm
Inorganic chemicals for reaction control mechanisms
34
% proteins in protoplasms
10-20%
35
Proteins in cell function
1. cytoskeleton (microtubules) 2.Functional proteins
36
Lipid components in cell
-Phospholipids and cholesterol -Triglycerides in fat cells
37
Carbohydrate components of cell
Glycogen Carbs provide cell nutrition
38
Cell membrane physical structures
-lipid bilayer -hydrophilic and hydrophobic domains -integral peripheral proteins -channel protein, carriers, enzymes, receptors -Carbs (glycocalyx)
39
Lipid bilayer consists of
Sphingoloids, phospholipids, cholesterol
40
Carbohydrate roles in cell membrane (4)
-Negatively charged, repels other neg charges -attachment -Receptors for hormones -immune reactions
41
Rough Endoplasmic reticulum role
Produces Proteins
42
Smooth endoplasmic reticulum role
Produces Lipids
43
Proteins are processed in
Matrix of the endoplasmic reticulum -crosslinked -folded -glycosylated (N-linked) -Cleaved
44
ER protein processing
Cleaved-->vesicles--> sent to golgi apparatus
45
Golgi apparatus
Receives transport vesicles from ER and processes them Substances are concentrated, sorted, and packaged for secretion
46
Golgi apparatus is composed of
4 or more stacked layers of flat vesicular structures
47
Lysosomes
digest - "stomach" of the cell Contain hydrolytic enzymes (hydrolases) to process proteins
48
Examples of hydrolytic enzymes in lysosomes
-phosphateses -nucleases -proteases -lipid degrading enzymes
49
Proteins are metabolized to
Amino Acids
50
Glycogen is metabolized to
Glucose
51
Lipids are metabolized to
fatty acids and glycerol
52
Lysosomes are formed from
budding golgi
53
Peroxisomes
oxidases (oxidizes poisonous substances using hydrogen peroxide) Self repliative
54
Secretory vesicles role
Store protein proenzymes i.e. digestive tract enzymes
55
Mitochondria
Powerhouse, produces ATP site of oxidative phosphorylation (to make ATP) self replicative
56