Week 9 Antitubuler Flashcards

1
Q

Antitubercular drugs cause

A

caused by acid fast bacillus mycobacterium tuberculosis

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2
Q

How is TB spread

A

Transmitted from person to person by droplets disbursed in the air through coughing and sneezing

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3
Q

Symptoms of TB

A

Anorexia, cough, sputum production, fever, night sweats, weight loss, and positive sputum

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4
Q

What type of drug is more effective on TB

A

Multi drug therapy (2 phases)

First initial face lasts 2 months while second last 4-7 months

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5
Q

Isoniazid use

A

Tread TB, prophylactic measure against TB by inhibiting bacterial cell wall synthesis and metabolized in liver

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6
Q

SA to isoniazid

A

NVC, drowsiness, tremors, rash, blurred vision, photosensitivity, tinnitus dizziness, dry mouth

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7
Q

Adverse reaction to isoniazid

A

Psychotic behavior, peripheral neuropathy, VTB6 deficiency

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8
Q

Rifampin what to know

A

Turns the urine an orange and soft contact me be permanently discolored

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9
Q

Mucosos

A

Infection caused by a fungus could be superficial or systemic

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10
Q

Oportunistic

A

Occurs in the immuno compromised or debilitated population

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11
Q

Non opportunistic

A

Histoplasmosis and blastomycosis

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12
Q

Systemic antifungals

A

Lungs, CNS, abdomen and usually transmitted through inhalation into lungs from dust, soul, or animal droppings

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13
Q

Superficial infections

A

Acquired by contact:
Mucous membranes, hair, nails, moist skin, overgrowth of normal flora flow wining ABC cause superficial fungal infections

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14
Q

Antifungals

A

Also known as antimycotic

Either fungistatic or fungicidal depending on the sustainability of the fungus and the dosage

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15
Q

Fluconazole

A

Effective against Candidasis

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16
Q

Fluconazole use

A

Against Candida infections but increase permeability of fungal cell membrane

17
Q

Fluconazole drug food interaction

A

Increase PY when taking Warfarin and increases hypoglycemia when taken with oral sulfonylureas

18
Q

Side effects to Fluconazole

A

NVDA h/a, stomach cramping

19
Q

Nystatin

A

PO or topically to td Candida infection

Poorly absorbed the other G.I. tract oral only given for intestinal candidiasis

20
Q

Metronidazole (flag)

A

Used to treat various disorders of the G.I. tract serious gram-negative infections

Avoid ETOH

21
Q

Viruses

A

Intracellular organism that uses the cell to reproduce by using their DNA and RNA to generate more viruses

22
Q

Influenza

A

Highly contagious viral infection that affects the nose throat and lungs with an abrupt onset

23
Q

Influenza a

A

Causes a mod to severe infection

24
Q

Influenza B

A

Usually causes mild illness in children

25
Q

Influenza C

A

Very rare in humans

26
Q

Acyclovir use

A

Against HSV1/2 by interfering with viral synthesis of DNA

elimination in iron and breast milk

27
Q

Acyclovir rug food reaction

A

Increase nephro neurotoxicity with aminoglycocides

28
Q

SE and AR acyclovir

A

NVD, HA, rash, tremors, lethargy

Ar: urticaria, anemia, gingival, hyperplasia, neuropathy, seizures, nephrotoxicity, bone marrow depression

29
Q

Hepatitis B

A

Serious liver infection caused by hepatitis B virus transmission is usually via needlestick, intimate sexual contact, childbirth

Found in all body fluids

30
Q

Hepatitis B SE

A

NVD, jaundice, malaise, and mygalgia

31
Q

Gamma globulin

A

Rich and antibodies found in the blood and provides passive immunity to a virus by blocking the penetration of a virus into the host cell
Given IM/IV

32
Q

Antimalarial drugs SE/AR

A

G.I. upset, cranial nerve VIII involvement, renal impairment, and cardiovascular effects

33
Q

Helmienths

A

Parasitic worms that feed on host tissue most common seen in intestines