Week 8a: acid base balance Flashcards
normal pH
7.35-7.45
normal PaO2
80-100mmHg
normal PaCO2
35-45
HCO3
21-25mmol/L
Normal base excess
-2 - +2
high anion gap =
acidosis
base excess more than +2 =
metabolic alkalosis
base excess less than -2 =
metabolic acidosis
normal anion gap
8-16mmol/L
signs and symptoms of metabolic acidosis
- increased respiratory rate and depth
- acidic urine
- weakness, fatigue, nausea and vomiting
- later signs: decreased LOC, decreased CO, coma and death
for treatment of metabolic acidosis, why is sodium bicarbonate not always indicated?
it can cause hyperosmolarity and hypoxia
what is the primary disturbance in metabolic acidosis?
decrease in bicarbonate, DKA, sepsis, severe diarrhea, renal failure, shock
respiratory compensation in metabolic acidosis?
hyperventilation to decreased PCO2
renal compensation in metabolic acidosis?
if no renal disease, then increased H+ excretion and increased HCO3 reabsorption
what is the primary disturbance in metabolic alkalosis?
decrease in bicarbonate
respiratory compensation in metabolic alkalosis?
hypoventilation to increase PCO2