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NURS 416 > Week 1 > Flashcards

Week 1 Flashcards

1
Q

Increased temp, heart rate, respirations and restlessness are typical sign of which emergency?

A

thyroid storm

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2
Q

Individuals with hypothyroidism may have prolonged and exaggerated responses to?

A

opioids

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3
Q

What is the only antithyroid medication that can be given in the first trimester of pregnancy?

A

propylthiouracil (PTU)

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4
Q

galactorrhea, amenorrhea, irregular menses, menses with infertility, and decreased libido and partial or complete impotence or infertility in men can be due to?

A

a prolactinoma and more specifically its inhibitory effects on the hypothalamic-pituitary-gonadal axis

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5
Q

what is a cause of gigantism or acromegaly?

A

growth hormone secreting adenoma

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6
Q

growth-hormone has ____ like effects

A

insulin

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7
Q

growth hormone is made in the?

A

anterior pituitary gland

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8
Q

Growth hormone deficiency in children:

A
  • interferes with linear bone growth

- results in short stature or dwarfism

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9
Q

growth hormone excess in children:

A
  • results in increased linear bone growth

- gigantism

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10
Q

emotional disturbances can lead to ___ _____ causing psychosocial dwarfism

A

functional hypopituitarism

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11
Q

what can occur in neonates with congenital GH deficiency?

A

hypoglycaemia and seizures

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12
Q

if ACTH deficiency in congenital GH deficiency is also present _____ is more severe

A

hypoglycaemia

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13
Q

how is the treatment for congenital GH deficiency administered

A

rhGH is administered by daily SC injection during the period of active growth and can be continued into adulthood

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14
Q

higher prevalence of atherosclerotic plaques and endothelial dysfunction, central adiposity, insulin resistance, dyslipidemia and increased high-sensitivity C-reactive protein and signs of?

A

Growth hormone deficiency in adults and contributes to cardiovascular mortality

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15
Q

what is the most common cause of acromegaly?

A

somatotrope (GH) adenoma

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16
Q

What are the 3 treatments for acromegaly?

A
  • somatostatin analogs
  • dopamine agonists
  • growth hormone receptor antagonists
17
Q

what is one important cause of precocious sexual development

A

adrenal disease

18
Q

Gonadotropin releasing hormone analogues

A

initially increase the production of FSH and LH by the pituitary, but then GnRH receptors on the pituitary down-regulate leading to decreased responsiveness to GnRH. This can help treat endometriosis, central precocious puberty and advanced prostate cancer.

19
Q

therapeutic effects and uses of Somatropin

A
  • growth failure in children due to GH deficiency
  • growth failure in children due to renal insufficiency
  • short stature associated with Turner syndrome
  • adult growth hormone deficiency
  • muscle wasting related to conditions including aids
20
Q

adverse effects of somatropin

A
  • insulin resistance, hyperglycaemia
  • hypothyroidism
  • hypertension
  • arthralgia, myalgia
  • headache
21
Q

a syndrome of polyuria resulting from the inability to concentrate urine and therefore to conserve water as a result of a lack of vasopressin (ADH) action

A

diabetes insipidus

22
Q

what are signs and symptoms of excessive fluid retention?

A
  • headache
  • restlessness
  • drowsiness
  • coma
23
Q

Low TSH is?

A

below 0.4 and indicative of a overactive thyroid

24
Q

Normal reference range of TSH?

A

0.3/0.5 - 3/5

25
Q

High TSH is?

A

above 5 and indicative of an underachieve thyroid

26
Q

which drugs will increase the metabolism of synthroid?

A
  • barbiturates
  • glucocorticoids
  • phenytoin
  • Zoloft
  • St Johns wort
27
Q

what are some adverse effects of propylthiouracil

A

leukopenia, myelosuppression, agranulocytosis, thrombocytopenia

28
Q

what is the most common thyroid neoplasm?

A

follicular adenoma

NURS 416 (17 decks)

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