Week 7 Neuromuscular pharm Flashcards
What are two adverse effects with levaodopa in terms of how they affect motor function?
- On/off effect
- wearing off effect
What med to we give to help with the wearing off effect?
Selegiline (Depreynyl)
What are the adverse effects of Levadopa?
Dyskinesia * - long term
orthostatic hypotention
CNS issues
Dark sweat & urine
how do we help lessen dyskinesias?
reduce the dose
What medications do we give for levadopa “off” times?
Selegiline
pramipexole
What is the adverse affect of levadopa + selegiline?
BP skyrockets - hypertensive crisis
what is the adverse effect of levadopa + carbidopa?
increased dyskenesia
increased psych disturbences
what is the adverse effects of levadopa + pramipaxole?
increased orthstatic hypotension
increased dyskenesias
hallucinations
If we want to increase motor function what med to we give?
levadopa
If we are worried about dyskinesis what med should be given instead of levadopa?
pramipraxole
What med do we not give to older adults?
pramiprexole
Which med controls motor function the best?
levadopa
What are the adverse effects of pramipexole?
Sleep attacks
impulse control issues in young people
orthostatic hypotension
hallucination
What does levodopa do in the body?
converts to dopamine in the brain
Why does carbidopa help levadopa?
It lessens the destrcution of levadopa so more can make it to the brain
