week 5 review

Question 1

If the results for serological markers include:
HBsAg +
Anti-HBs =
Anti-HBc (total) +
HBeAg +
Anti-HBe =
What would that indicate?

Answer 1

chronic hep B, active replicating

Question 2

This type of jaundice is associated with excessive destruction of RBCs without elevation of ALT levels.

Answer 2

pre-hepatic
-> no damage to liver but bilirubin accumulation

Question 3

This is a liver disease characterized by a defective conjugation system and it affects 5% of the population of the U.S.

Answer 3

Gilberts syndrome

Question 4

What is the target organ for an infant with kernicterus?

Answer 4

brain

Question 5

A GFR of 15mL/min/m2 or less, creatinine clearance of <10mL/min, BUN of >50 mg/dL, creatinine >3 mg/dL, potassium > 6.5 mEq/L, and hemoglobin <10 g/dL are all lab test values indicative of what disease state?

Answer 5

kidney failure
- a GFR <15 indicates full renal failure

Question 6

When only the glomerulus has been damaged, ______ proteins can pass through the glomerular membrane to be excreted in urine when it couldn’t before the damage.

Answer 6

large (high molecular weight)

Question 7

The glomeruli and proximal and distal tubules are located in the renal _____.

Answer 7

cortex

Question 8

What is the proper order of structures of a nephron from the blood to the collecting duct?

Answer 8

Glomerulus, proximal tubule, loop of Henle, distal tubule