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Clinical Chem 2 > hepatitis > Flashcards

hepatitis Flashcards

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1
Q

define hepatitis

A

inflammatory condition of the liver

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2
Q

most common viral cause of hepatitis

A

HAV, HBV, HCV< HDV, HEV

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3
Q

symptoms with acute hepatitis

A
  • jaundice
  • dark urine
  • fatigue
  • nausea
  • vomiting
  • abdominal pain
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4
Q

with what hepatitis is chronic hepatitis seen

A

HBV and HCV

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5
Q

hepatitis A

A
  • infectious hepatitis
  • most common
  • nonenveloped RNA
  • contaminated food and water
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6
Q

Hepatitis B

A
  • both acute and chronic infections
  • long term environmentally stable
  • DNA virus
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7
Q

HBcAg

A

core virus

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8
Q

HBsAg

A

surface antigen on surface proteins

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9
Q

HBeAg

A

envelope antigen

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10
Q

what does the presence of HBsAg indicate

A

present before clinical symptoms start

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11
Q

Anti-HBs

A

hep B surface antibody
pos = aquired immunity
neg = inadequate immune response or lack of recovery

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12
Q

HBcAg

A

only present in nuclei of hepatocyte during acute infection

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13
Q

anti-HBc total

A

used for recent HBV infections
differentiates recent vs chronic HCV

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14
Q

anti-HBc IgM

A

specific for acute HBV infection

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15
Q

what do the results indicate
HBsAg pos
total anti-HBc pos
IgM anti-HBc pos

A

acute infection

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16
Q

what do the results indicate
HBsAG pos
total anti-HBc pos

A

chronic infection

17
Q

results for chronic Hep B actively replicating

A

HBsAG pos
anti-HBs neg
anti-HBc total pos
HBeAg pos
anti-HBe neg

18
Q

results for chronic hep B non replicating

A

HBsAg pos
Anti-HBs neg
Anti-HBc total pos
HBeAg neg
anti-HBe pos

19
Q

hepatitis C

A

RNA
chronic
parentally transmitted

20
Q

chronic HCV

A

develops in 80% of infected
anti-HCV by EIA detection then RNA

21
Q

hepatitis D

A

delta hepatitis
defective RNA
requires HBV infection

22
Q

difference between coinfection and superinfection

A

coinfection = at the same time
superinfection = D after B

23
Q

hepatitis E

A

nonenveloped RNA
fecal-oral infection and waterborne
IgM diagnosis

24
Q

which hepatitis is the only DNA virus

A

HBV

25
Q

which hepatitis cannot form a chronic infection

A

hep A

Clinical Chem 2 (25 decks)

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