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Clinical Chem 2 > exam 3 old qs > Flashcards

exam 3 old qs Flashcards

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1
Q

which could account for drug toxicity following a normally prescribed dose to the geriatric patient?
- decreased real clearance
- slowing of drug absorption
- liver impairment
- all of the above

A

all of the above

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2
Q

all of the following represent normal physiology of the newborn except:
- weight of 2.1 kg
- immature liver function and inability to eliminate excess bilirubin
- infants normally rapidly adapt by initiating active respiration
- 4-6months for infants body weight to double

A

weight of 2.1 kg

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3
Q

which of these statements are true
- regular exercise can improve the quality of life among geriatric pt
- excersise can help prevent depression and other diseases
- proper nutrition is importnat along with excersise
- all of the above are true

A

all of the above

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4
Q

which test would be likely to show an increase in value in geriatric patients
- calcium
- testosterone
- ANAs
- aldosterone

A

ANAs

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5
Q

which of the following conditions are related to acidosis in the pediatric patient
- anoxia and trauma during delivery
- respiratory distress syndrome
- hyperammonemia caused by liver disease
- hyperventilation

A

anoxia and trauma during delivery
- also accepted respiratory distress syndrome

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6
Q

which of the following biomarkers are found in high concentratins in neonates as compared to adults
- creatinine
- ammonia
- uric acid levels
- total Igs

A

ammonia

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7
Q

what are special considerations that need to be taken into account with regard to neonatal blood collections (select all that apply)
- sample should be kept on ice
- minimize evaporation of sample from open tubes
- should be processed on large automatin
- sample vol should be minimized to reduce blood loss

A
  • minimize evap
  • small vol minimize blood loss
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8
Q

which of the following choices is FALSE concerning blood obtained by heel stick (capillary) and venipuncture (venous)?
- chemical comp of the sera derived from each is identical
- the capillary specimen is likely contaminated with interstitial fluid
- venous blood contains higher bilirubin and calcium concentraitns
- capillary blood contains less concentrated proteins due to mixing with intersitial fluid

A

checmical comp of sera from each is identicle

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9
Q

true or false
specimens for porphyrin testing do NOT need to be protected from light

A

false

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10
Q

match the porphyria with its symptom type: acute intermittent porphyria (AIP)
- neuropsychiatric
- cutaneous
- neurocutaneous

A

neuropsychiatric

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11
Q

match the porphyria with its symptom type: Erythropoietic protoporphyria (EPP)
- neuropsychiatric
- cutaneous
- neurocutaneous

A

cutaneous

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12
Q

match the porphyria with its symptom type: Variegate porphyria (VP)
- neuropsychiatric
- cutaneous
- neurocutaneous

A

neurocutaneous

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13
Q

match the porphyria with its symptom type: Congenital erythropoietic porphyria (CEP)
- neuropsychiatric
- cutaneous
- neurocutaneous

A

cutaneous

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14
Q

which statement about secondary porphyrinurias is NOT true
- can be caused by liver disease and heavy metal poisoning
- inherited disorders of bilirubin metabolism
- inherited condition associated wiht increased excretion of urinary porphyrins
- not due to an inherited defect in heme syntehsis

A

are an inherited condition associated with increased exretion of urinary porphyrins
- secondary = not inherited

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15
Q

true or false
the aqueous solubility of porphyrins varies with the number of carboxylic acid substitutes present in that particular porphyrin

A

true
- more carboxy = more soluble

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16
Q

how many pyrrol erings make up a porphyrin ring

A

4

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17
Q

this is chelated to the porphyrin ring to form heme
- calcium
- iron
- oxygen
- Carbon dioxide

A

iron

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18
Q

which type of porphyria is NOT considered chronic
- hereditary coproporphyria (HCP)
- congenital erythropoietic porphyria (CEP)
- erythropoietic porphyria (EPP)
- porphyria cutanea tarda (PCT)

A

hereditary coproporphyria (HCP)
- neurocutaneous
- all cutaneous = chronic

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19
Q

which of the following is a qualitative screening test for porphobilinogen that may be performed to aid in the diagnosis of the porphyria
- caraway
- gutman
- jendreassik-grok
- watson-schwartz

A

watson-schwarts

20
Q

the most common abnormalities in the structure of hemoglobin is:
- amino acid deletions
- elongated hemoglobin chains
- fused or hybrid chais
- amino acid substitutions

A

amino acid substitutions

21
Q

name the order (slowest to fastest) on cellulose acetate
- hgb F,S,C,A

A

in order
(slow) C
S
F
(fast) A

22
Q

this area of the pancreas becomes affected by cancer there is high potential that it will go undetected and lead to greater morbidity and mortality in the patient.
- head
- body
- neck
- tail

A

tail
- must migrate from tail through body to head to detect

23
Q

which of the following is NOT true regarding normal pancreatic fluid
- it is clear, colorless and watery
- it contains a high concentratin of hydrochloric acid
- it maintains an alkaline pH
- it has the same concentratin of potassium and sodium as serum

A

it contains a high concentration of hydrocholoric acid
- high concentration of sodium bicarb to neutralize stomach acid

24
Q

the hormone responsible for the release of bile into the intestines and the secretion of enzymes is:
- cholecystokinin
- secretin
- ghrelin
- pancreatic polypeptide (PP) hormone

A

cholecystokinin (CCK)

25
Q

true or false
the exocrine function of the pancreas includes the production of insulin and glucagon

A

false
- describes endocrine

26
Q

the recommended specimen requirement for steatorrhea is a :
- 12 hr stool colleciton
- 24 hr stool
- 48 hr stool
- 72 hr stool

A

72 hour

27
Q

true or false
in patients with exocrine pancreatic insufficiency, fecal fat is often decreased an fecal enzymes are increased

A

false

28
Q

true or false
the ampulla of vater si where the pancreas and stomach join together

A

false
- pancreatic duct and common bile duct

29
Q

name the hormone secreted from each cell type:
- alpha
- beta
- delta
- gamme
- epsilon

A
  • alpha: glucagon
  • beta: insulin
  • delta: somatostatin
  • gamma: PP hormone
  • epsilon: ghrelin
30
Q

true or false
the acinar cells produce hormones in the pancreas

A

false

31
Q

this test may be used becauase it is a non-invasive, indirect indicator of moderate and severe exocrine pancreatic dysfunciton
- fecal fat - sudan staining
- feco chymotrypsin
- fecal elastase-1
- cholecystokinin

A

fecal elastase -1

32
Q

true or false
there are no associated risks with using TPN for patients who need it

A

false

33
Q

true or false
since they are stored, water soluble vitamins have greater risk of toxicity

A

false
- they are not stored in fat

34
Q

which of these vitamins is water soluble? select al lthat apply
- vitamin B6
- vitamin D
- vitamin A
- vitamin C
- vitamin K

A

B6 and C

35
Q

This deficiency in this vitamin is associated with hair loss, anorexia, and depression. It is often found in hair products and supplements. Taking supplements that contain this may cause interference with certain test assays.

A

B7 biotin

36
Q

select the two most common test run to differentiate the reason behind a diagnosis of megaloblastic anemia
- folate
- D
- B6
- B12

A

folate and B12

37
Q

if you had the following lab results what condition would you expect to see:
- transferrin increased
- ferritin decreased
- % sat decreased
- TIBC increased

A

iron deficiency

38
Q

which iron test matches the description:
The theoretical amount of iron that could be bound if transferrin in the plasma was saturated

A

TIBC

39
Q

which iron test matches the description:
The major iron storage protein for the body

A

ferritn

40
Q

which iron test matches the description:
The primary plasma iron transport protein

A

transferrin

41
Q

which iron test matches the description:
The Fe3+ bound to transferrin

A

serum iron

42
Q

given the description, which spectroscopy matches:
Quantification of an element by measuring the intensity of emitted radiation from an aerosolized sample
- atomic emission spectroscopy
- atomic absorption spectroscopy

A

atomic emission spectroscopy

43
Q

given the description, which spectroscopy matches:
Determination of element quantity through the absorption of optical radiation by free atoms in the gas phase
- atomic emission spectroscopy
- atomic absorption spectroscopy

A

atomic absorption spectroscpy

44
Q

This element is widely used in industrial and household ways, and interferes with enzyme activity. It is associated with encephalopathy, anemia, bone disease and progressive dementia. It is excreted mainly in the urine.
- copper
- aluminum
- cadmium
- arsenic

A

aluminum

45
Q

An employee at a local glass blowing and manufacturing facility is admitted to the Psychiatric Hospital due to severe anxiety and constant bouts of compulsive laughing and crying. Given these symptoms, what kind of heavy metal toxicity should be expected?
- manganese
- mercury
- molybdenum
- selenium

A

manganese

46
Q

Over the decades, this element has been considered a toxic element, a carcinogen, essential element, and an anti-carcinogen. It is also involved in the metabolism of thyroid hormones.
- selenium
- zinc
- copper
- molybdenum

A

selenium

47
Q

This heavy metal has both an essential form and a toxic, nonessential form. When absorbed it will be bound by transferrin and transported by albumin.
- chromium
- cadmium
- copper
- aluminum

A

chromium

Clinical Chem 2 (25 decks)

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