Week 5 (part 1) Flashcards

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1
Q

Deoxyribonucleic acid

A

Genetic material of all cells, sugar phosphate backbone with nucleic acid bases and polymer of nucleotides each with a sugar phosphate and nucleic acid base

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2
Q

Bases

A

Thymine
Adenine
Cytosine
Guanine

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3
Q

DNA replication

A

Separate strands then DNA polymerase uses each strand as a template to add complementary strand

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4
Q

DNA polymerase

A

Works it way across the strands and brings complementary nucleotides

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5
Q

Gene expression

A

DNA -> RNA -> Protein -> trait

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6
Q

RNA

A

Typically single stranded, different sugar, uracil rather than thymine

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7
Q

3 types of RNA

A

Messenger RNA, transfer RNA and ribosomal RNA

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8
Q

Messenger RNA

A

Carries protein blueprint from DNA to ribosomes

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9
Q

Transfer RNA

A

Carries amino acids to ribosomes

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10
Q

Ribosomal RNA

A

With certain proteins makes up ribosomes

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11
Q

Inherited diseases are caused by

A

The recessive allele

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12
Q

Sex linked

A

Genes with their loci on the sex chromosomes

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13
Q

X linked

A

Genes with their loci on the X chromosome

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14
Q

Population genetics

A

Concerned with how common certain genotypes are in a population rather than the genotypes of specific parents and their offsprings

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15
Q

The probability that any X chromosome carries an allele for red green colour blindness is 8%, what is the probability that a female can be colour blind

A

0.08 x 0.08 = 0.0064

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16
Q

Transcription

A

DNA -> Coding strand -> template strand -> transcript

17
Q

Translation

A

Transcript -> polypeptide

18
Q

RNA polymerase

A

Makes RNA by reading DNA

19
Q

Three phases

A

1) initiation
2) elongation
3) termination

20
Q

Primary structure

A

The peptide sequence define at DNA level

21
Q

Secondary structure

A

The shape of a specific loci pattern of amino acids

22
Q

Tertiary structure

A

The shape of folded protein

23
Q

Quaternary structure

A

A two or more proteins which together make up a unit

24
Q

Gene regulation

A

Control of transcription is the most important mechanism in the control of gene expression

25
Q

Lac operon

A

DNA codes for certain proteins that are involved in the use of lactose

26
Q

Negative control

A

Something must be removed to allow transcription (repressors)

27
Q

Positive control

A

Something must be added to allow transcription (activators)