Week 3 embryo Flashcards
3 facts about the embryonic period
- 3-8 weeks of development
- time of greatest organogenesis
- stage when most susceptible to teratogens
primitive streak formed by epi or hypoblasts?
epiblasts
primitive streak defines which axis of the embryo?
cranial- caudal
epiblasts travel through ___ to make mesoderm and endoderm
the primitive groove, where epiblasts displace hypoblast layer to form ectoderm and fill in the space between the two layers to make mesoderm/ mesenchyme
gastrulation occurs in week…
3
2 places where there is no mesoderm
oropharyngeal membrane and cloacal membrane
ectoderm and endoderm are tightly fused here.
notochord is made by ____ cells
mesenchymal cells that proliferate from the primitive node
what does the notochord form in the adult?
nucleus pulposus of vertebral bodies
a few facts about the notochord
defines cranial-caudal axis
primary inductor of embryo
forms the nucleus pulposus in adults
induces ectoderm to form the neural plate
made of mesenchymal cells
neural tube forms by…
proliferation of ectoderm cells that invaginate and fold on each other
induced by the notochord
3 parts of mesoderm
paraxial mesoderm
intermediate mesoderm
lateral mesoderm
paraxial mesoderm derivatives
somites (give rise to axial skeleton- skull and vertebrae, muscles, and dermis)
lateral mesoderm derivatives
somatic layer- body wall
splanchnic- embronic gut wall
2 neuropores of neural tube
- rostral
2. caudal
failure of rostal neuropore to close
anacephaly- brain is exposed :(