Week 3 embryo Flashcards

1
Q

3 facts about the embryonic period

A
  1. 3-8 weeks of development
  2. time of greatest organogenesis
  3. stage when most susceptible to teratogens
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2
Q

primitive streak formed by epi or hypoblasts?

A

epiblasts

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3
Q

primitive streak defines which axis of the embryo?

A

cranial- caudal

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4
Q

epiblasts travel through ___ to make mesoderm and endoderm

A

the primitive groove, where epiblasts displace hypoblast layer to form ectoderm and fill in the space between the two layers to make mesoderm/ mesenchyme

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5
Q

gastrulation occurs in week…

A

3

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6
Q

2 places where there is no mesoderm

A

oropharyngeal membrane and cloacal membrane

ectoderm and endoderm are tightly fused here.

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7
Q

notochord is made by ____ cells

A

mesenchymal cells that proliferate from the primitive node

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8
Q

what does the notochord form in the adult?

A

nucleus pulposus of vertebral bodies

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9
Q

a few facts about the notochord

A

defines cranial-caudal axis

primary inductor of embryo

forms the nucleus pulposus in adults

induces ectoderm to form the neural plate

made of mesenchymal cells

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10
Q

neural tube forms by…

A

proliferation of ectoderm cells that invaginate and fold on each other

induced by the notochord

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11
Q

3 parts of mesoderm

A

paraxial mesoderm

intermediate mesoderm

lateral mesoderm

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12
Q

paraxial mesoderm derivatives

A

somites (give rise to axial skeleton- skull and vertebrae, muscles, and dermis)

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13
Q

lateral mesoderm derivatives

A

somatic layer- body wall

splanchnic- embronic gut wall

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14
Q

2 neuropores of neural tube

A
  1. rostral

2. caudal

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15
Q

failure of rostal neuropore to close

A

anacephaly- brain is exposed :(

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16
Q

failure of caudal neuropore to close

A

spina bifida- spinal cord exposed to amniotic fluid and is damaged

17
Q

derivative of neural tube

A

brain and spinal cord

18
Q

neural crest cell derivatives

A
DRG
ganglia of ANS
adrenal glands
cranial nerves
facial muscles
melanocytes
19
Q

intraembryonic coelom formed by the ___ mesoderm

A

lateral

20
Q

intraembryonic coelom becomes the…

A

pericardial cavity
pleural cavity
peritoneal cavity

21
Q

angiogenesis begins in the…

A

extraembryonic mesoderm

yolk sac

connecting stalk

chorion

and grows towards the embryo

22
Q

what are blood islands?

A

extraembryonic mesenchymal cells that aggregate

23
Q

cardiac mesenchyme forms 3 things:

A
  1. aorta
  2. pulmonary a.
  3. heart
24
Q

when does the heart begin to beat?

A

week 3, making it the first functional organ in the embryo