Embryo heart Flashcards
Cardiovascular system derived from which germ layer?
mesoderm
CV system forms in which embryonic body cavity?
intraembryonic coelom
Pharyngeal endoderm induces mesoderm to form..
blood islands and cardiac myocytes in the intraembryonic coelom
Where does the cardiogenic area start off at?
anterior to the oropharyngeal membrane- moves to thorax with cranial folding
Angiogenic cords from cardiogenic mesoderm are precursors to what?
paired heart tubes –> aorta and heart
Vitelline, umbilical, and cardinal arteries and veins empty at…
caudal end of fetus
The heart tube is precursor to…
aortic sac, truncus arteriosus, bulbis cordis, primitive ventricle, primitive atrium, sinus venosus
Endocardial cushions important for…
Partitioning primitive atrium and ventricle,
Partitioning of R and L AV canals, role in formation of AV valves
Circulation in primitive heart:
umbilical v (high O2), cardinal v (low O2), vitelline v (low O2) –> sinus venosus –> atria –> ventricle –> bulbus cordis –> truncus arteriosus –> aortic arches –> dorsal aorta –> body and placenta
primitive atria are divided by 2 septa
- septum primum
2. septum secundum
interventricular septum
thick mesodermal tissue that grows towards endocardial cushions
caused by differential (fast) growth of cells in the IV septum region
2 parts of interventricular septum
membranous- forms at bulbar ridges
muscular
foramen primum
formed near the endocardial cushions as the septum primum grows towards the endocardial cushions
foramen secundum
formed by fenestrations of septum primum
foramen ovale formed in which septum?
formed in the septum secundum
covered by flap of septum primum
role of foramen ovale
shunts blood from R –> L atrium
allows blood to bypass lungs
when does foramen ovale close and how does it exist in the adult?
closes at birth when L atrium pressure increases and pulmonary vascular resistance decreases
remains as fossa ovalis
patent foramen ovale
occurs when flap of septum primum does not close