Week 3 - Adaptive Immunity Flashcards
Define Immunity
Capacity of the immune system to successfully defend the body against a potentially infectious agent
What cells are involved in adaptive immunity?
Lymphocytes
What are the 2 types of lymphocytes?
- B cells
- T cells
Where do both types of Lymphocytes originate from?
Stem cells in bone marrow
What is an Antigen?
Any substance that the body recognises as foreign, or non-self
Name the two categories of adaptive immunity
- Anti-body mediated immunity
- Cell-meditated immunity
Describe ‘Anti-body meditated immunity’
- This response activates B-cells that then proliferate and produce:
- Plasma cells
- Memory cells - Involves the activation of B cells and secretion of antibodies when in contact with a pathogen.
- Produces antibodies to destroy microbes
Describe ‘Cell-meditated immunity’
- Destroys infected cells
- Immune response that does not involve antibodies.
What cells are involved in ‘anti-body meditated immunity’?
- B cells
- Plasma
- Memory
What cells are involved in ‘cell-meditated immunity’?
- T cells
- Memory-T cells
How do B cells provide immunity?
Fight bacteria and viruses by making Y-shaped proteins called antibodies, which are specific to each pathogen and are able to lock onto the surface of an invading cell and mark it for destruction by other immune cells
How do Plasma cells provide immunity?
Produce antibodies which circulate in the blood and other body fluids which target bacteria and their toxins and prepare them for destruction, also target viruses before they enter body cells
How do Memory cells provide immunity?
Persist in the body for months - years and can react with the same antigen again if it enters the body at a later date
How do T cells provide immunity?
Destroy cells that harbour viruses or bacteria and cancer cells and parasites. They fight intracellular pathogens
How do Memory T cells provide immunity?
Specifically produced to the microbe