Week 225 Malignant Melanoma Flashcards
Week 225
What is the most common commensal bacteria on skin?
Staph Epididimis (>90% in some areas)
Week 225
Which bacteria is associated with acne?
Propiniobacterium Acnes
Week 225
Which type of exotoxin can cause scalded skin syndrome?

Exfoliative Exotoxins - these break down dermasones.
Week 225
Which Exotoxins cause Toxic Shock syndrome?
Superantigens. Threse bind irreversibly to T cells, producing hyperactivtion and increased cytokine production.
Week 225
Which types of infections tend to be caused by Streptococcus Pyogens?
- Deeper spreading infections with systemic symptoms
- Ecthyma
- Erisypelas
- Cellulitis
- Necrotising Fasciitis
Week 225
Which bacteria is the usual cause of Impetigo?

- Staph. Aureus - Localised infection confined to the epidermis (this is why it doesn’t scar).
- V contagious
- Rarely causes systemic symptoms
Week 225
What condition is this?

Impetigo
Week 225
What is Bullous impetigo?
- Painless, fluid filled blisters
- Caused by exfoliative toxin
- Blisters may have pruritic skin around them
Week 225
What is this infection?

- This is Ecthyma
- Localised infection which spreads to dermis - DOES scar
- Crusted/ulcerated lesions
- mostly on legs
Week 225
Which bacteria usually causes Ecthyma?
Strep. Pyogens.
Week 225
What is folliculitis?
Superficial Infection of 1+ Hair follicles
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What is a Furuncle?
This is a boil. A small abscess formed from 1+ infected hair follices and sebaceous glands.
Week 225
What is a Carbuncle?
- Large deep abscess formed from a group of contigious follicles.
- Usually caused by Staph Aureus
Week 225
What is topical Fusidic acid or Mupirocin used for?
Used for mild/local skin infections
Week 225
Which oral antibiotics are recommended for widespread infections caused by Staph Aureus?
- Flucloxacillin or Erythromycin
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What oral antibiotics are used for an infection caused by Strep. Pyogenes?
Penicillin OR Erythromycin
Week 225
What is this infection?

- This is Erysipelas
- Infection of dermis and subcut tissue
- Well demarcated, raised border
- Erythematous, hot swolen region
- May progress to systemic if not treated
Week 225
What is the difference between Erysipelas and Cellulitis?
- Cellultis is in subcut tissue only. This means that it is less well demarcated than Erysipelas.
- Likely progress to systemic symptoms
- Strep Pyogens likely cause of both
- Lymphangitis can occur in either
- Nephritis (rare) can occur in either
Week 225
Which condition is this?

This is necrotising Fasciitis. The large dark bullae are classical symptoms. If you leave it without surgical management, it gets this bad!

Week 225
What is the usual cause of Necrotising Fasciitis?
Strep pyogenes. USually gains access through prior trauma or lesions.
Week 225
Which age group does Scalded skin syndrome usually occur in?
Infants/young children
Week 225
What is the antibiotic treatment for Cellulitis or Erysipelas?
Flucloxacillin or Erythromycin
Week 225
What is the treatment for Necrotising Fasciitis?
Immediate surgical debridement, with IV Benzylpenicillin + Clindamycin + Gentamicin
Week 225
Corynebacteria are normal commensals, that can sometimes cause minor pathologies in moist areas. So what’s this?

This is Erythrasma. Hyperpigmented Macular patches. Pink on black skin, bron on white. Well demarcated, and lichenified (leathery skin).






















