Week 20: Psychopathology II Flashcards
What are mood disorders?
Extended periods of depressed, euphoric, or irritable moods that cause significant distress and interfere with daily life.
What is a major depressive episode (MDE)?
Symptoms that co-occur for at least two weeks and cause significant distress or impairment in functioning.
What are the core symptoms of a major depressive episode?
Core symptoms include:
* depressed mood
* diminished interest or pleasure in almost all activities
* significant weight loss or gain
* insomnia or hypersomnia
* psychomotor agitation or retardation
* fatigue or loss of energy
* feeling worthless or excessive guilt
* diminished ability to concentrate
* recurrent thoughts of death or suicidal ideation.
What is the duration requirement for a manic episode?
Must last one week or longer unless hospitalization is required.
What distinguishes a hypomanic episode from a manic episode?
Hypomanic episodes last at least four days and do not necessarily cause significant impairment in functioning.
What are the two major types of unipolar mood disorders?
- Major depressive disorder (MDD)
- Persistent depressive disorder (PDD; dysthymia).
What is the prevalence rate of major depressive disorder (MDD) in the U.S.?
Lifetime prevalence rate for MDD is 16.6%.
At what average age does major depressive disorder (MDD) typically onset?
The average age of onset is mid-20s.
What demographic factors influence the prevalence of MDD?
Gender, age, and socioeconomic status (SES).
How does gender affect the prevalence rates of MDD?
Women experience two to three times higher rates of MDD than men.
What is the lifetime prevalence rate of bipolar spectrum disorders in the U.S.?
Approximately 4.4%.
What are the three major types of bipolar disorders according to DSM-5?
- Bipolar I Disorder
- Bipolar II Disorder
- Cyclothymic disorder.
What is the common age of onset for bipolar disorders?
Adolescence is a significant risk period for BD.
What are common co-occurring disorders with bipolar disorder?
Anxiety disorders and substance use disorders.
What is perinatal depression?
Depression that occurs following childbirth, affecting about 5% of all mothers.
What percentage of people diagnosed with bipolar disorder (BD) will attempt suicide at least once?
Estimated 25%–50%.
What is the diagnostic criteria for persistent depressive disorder (PDD)?
Feeling depressed most of the day for more days than not for at least two years, along with at least two additional symptoms.
What is the relationship between socioeconomic status (SES) and MDD?
Higher prevalence rates of MDD are associated with lower SES.
True or False: The DSM-5 uses the term ‘mood disorders’ for classification.
False. It uses ‘Depressive Disorders’ and ‘Bipolar and Related Disorders.’
Fill in the blank: The World Health Organization ranks both major depressive disorder and ________ among the top 10 leading causes of disability worldwide.
[bipolar disorder]
What is the prevalence of Bipolar Disorder (BD) in older adults compared to younger adults?
1% in older adults vs. 4% in younger adults
(Merikangas et al., 2007)
What are some key factors implicated in the development of mood disorders?
Biological and psychosocial factors
These factors contribute to the onset and course of mood disorders.
What does MDD stand for?
Major Depressive Disorder
MDD is one of the most common mood disorders.
What role do genetic factors play in Major Depressive Disorder (MDD)?
Genetic factors are implicated in the development of MDD
Supported by family and twin studies.
What type of life events are strongly related to MDD?
Severe stressful life events
Such as divorce or unemployment.
True or False: Minor life events predict the first major depressive episode (MDE) more than subsequent episodes.
False
Minor events may play a larger role in subsequent episodes.
What is the primary focus of cognitive therapies for depression?
Helping patients identify and change distorted automatic thoughts
Based on cognitive-behavioral principles.
Which neurotransmitters are primarily targeted by antidepressant medications?
Dopamine, norepinephrine, and serotonin
These neurotransmitters are implicated in depression.
Fill in the blank: The first line treatment choice for Bipolar Disorder (BD) is _______.
lithium
What is a common side effect of lithium treatment?
Impaired cognitive function
Other side effects include nausea and weight gain.
What is Interpersonal and Social Rhythm Therapy (IPSRT) focused on?
Addressing sleep disruption
Aims to maintain a stable rhythm in patients’ lives.
What is the primary concern regarding antidepressant medications for patients with BD?
They can induce mania or hypomania
SSRIs and SNRIs are particularly noted for this risk.
What is the effect of positive life events on patients with BD?
Can adversely impact the course of BD
May lead to increased manic symptoms after achieving desired goals.
What is the mode of inheritance for Major Depressive Disorder (MDD)?
Not fully understood
No single genetic variation has been definitively linked.
What is the significance of attributional styles in the context of MDD?
Pessimistic attributional styles increase vulnerability
Internal, global, and stable attributions correlate with MDD risk.
What is a common treatment for severe depression that involves inducing a seizure?
Electroconvulsive therapy (ECT)
ECT is used for patients resistant to other treatments.
What is one of the main psychosocial treatments for depression?
Cognitive Behavioral Therapy (CBT)
Focuses on the interplay of thoughts, behaviors, and emotions.
What are some environmental factors that increase the risk for MDD?
- Early adversity (e.g., childhood abuse)
- Chronic stress (e.g., poverty)
- Interpersonal factors
These factors contribute to the onset and recurrence of depression.