Week 2: Inflammation

Question 1

body’s normal, protective to local injury

Answer 1

inflammation

Question 2

cells that travel trough BV to injured tissue that ___ and ___ __ damage

Answer 2

neutrophils, lymphocytes; kill, clean up

Question 3

inflammation can be destructive when it occurs in the ___ ___ or when it ___ ___ ____

Answer 3

wrong place, lasts too long

Question 4

four cardinal signs of inflammation (latin)

Answer 4

rubor, dolor, calor, tumor

Question 5

latin word for redness

Answer 5

rubor

Question 6

latin word for pain

Answer 6

dolor

Question 7

latin word for warmth

Answer 7

calor

Question 8

latin word for swelling

Answer 8

tumor

Question 9

four cardinal signs of inflammation (English)

Answer 9

redness, pain, warmth, swelling

Question 10

word part for inflammation

Answer 10

-itis

Question 11

causes of inflammation

Answer 11

• infection
• physical trauma
• chemical agents
• unidentified
• immune-stimulating agents

Question 12

acute inflammation
begins ____
over within __ hours
main cell: _____

Answer 12

immediately, 48 hours, neutrophils

Question 13

chronic inflammation
begins _____
can last _______
main cells (2): ___ ___

Answer 13

48 hours, days/weeks/years, lymphocytes and macrophages

Question 14

1st step in acute inflammation

1. ______
2. Neutrophils leave vessels, enter tissue
3. Neutrophils kill any foreign invaders/substances, then take off.

Answer 14

vessels constrict, then dilate

Question 15

why do vessels constrict in acute inflammation?

Answer 15

slow blood flow to area until hemostasis

Question 16

why do vessels dilate in acute inflammation?

Answer 16

allows cells inside BV to leave

Question 17

2nd step in acute inflammation

1. vessels constrict, then dilate
2. ________
3. Neutrophils kill any foreign invaders/substances, then take off.

Answer 17

Neutrophils leave vessels, enter tissue

Question 18

3rd step in acute inflammation

1. vessels constrict, then dilate
2. Neutrophils leave vessels, enter tissue
3. ________

Answer 18

Neutrophils kill any foreign invaders/substances, then take off.

Question 19

in vasodilation, endothelium lining ___ and becomes more ____

Answer 19

thins, permeable

Question 20

neutrophils have a ____ nucleus

Answer 20

segmented

Question 21

neutrophil extravasation

Answer 21

margination, rolling, binding, diapedesis

Question 22

margination is when a cell…

Answer 22

goes from middle of BV to the margins of the endothelial cell

Question 23

a cell leaves BV through epithelial through process of…

Answer 23

diapedesis

Question 24

two ways neutrophils kill things

Answer 24

degranulation, phagocytosis

Question 25

lots of neutrophils cause…

Answer 25

pus

Question 26

3rd step of chronic inflammation

1. macrophages eat things
2. lymphocytes fight any remaining foreign invaders
3. ________

Answer 26

both cells trigger the immune system (often unhelpful)

Question 27

2nd step of chronic inflammation

1. macrophages eat things
2. _______
3. both cells trigger the immune system (often unhelpful)

Answer 27

lymphocytes fight any remaining foreign invaders

Question 28

1st step of chronic inflammation

1. _______
2. lymphocytes fight any remaining foreign invaders
3. both cells trigger the immune system (often unhelpful)

Answer 28

macrophages eat things

Question 29

collection of macrophages/lymphocyte “ball” that occurs when a foreign substances/invader is really hard to eradicate

Answer 29

granulomatous inflammation

Question 30

granuloma with necrosis in the center

Answer 30

caseating granuloma

Question 31

bunch of macrophages joined together to make one big cell

Answer 31

multinucleated giant cells

Question 32

chronic inflammation can lead to bad things, such as…

Answer 32

cardiovascular disease, diabetes, cancer, autoimmune disease, pancreatitis, etc…..