Week 2 Antianginals

Question 1

What are the three common drug classes used to treat angina?

Answer 1

Nitrates
Beta-blockers
Calcium channel blockers

Question 2

What is the treatment goal for antianginal medications

Answer 2

Restore O2 supply to meet cardiac demand

Question 3

What actions do nitrates provide that reduce angina?

Answer 3

Decreased venous tone, decreased cardiac workload, vaso dilation of coronary arteries

Question 4

What actions do beta-blockers provide that reduce angina?

Answer 4

Decreased cardia workload and O2 demands by blocking the action of catecholamines. This decreased HR and BP

Question 5

What actions do Calcium channel-blockers provide that reduce angina?

Answer 5

Decreased cardiac workload and O2 demand by relaxing coronary artery spasm, peripheral arterioles, decreasing cardiac contractility, and decreasing peripheral resistance (decreasing afterload and workload)

Question 6

What order of antianginal medications is given with classic angina?

Answer 6

1. Nitrates
2. Nitrates+beta-blockers
3. Nitrates + beta-blockers + Calcium channel blockers
4. Coronary Bypass surgery

Question 7

What order of antianginal medications is given with variant angina?

Answer 7

1. Nitrates
2. Nitrates + Calcium channel blockers
3. Coronary bypass surgery