Week 2

Question 1

What are (3) general uses of drugs?

Answer 1

• Replacing Body Deficiency
• Altering with Cell Function
• Ridding the Body of Invading Microbes or Abnormal Cells.

Question 2

Things that are made inside the body in normal function are ________?

Answer 2

Endogenous

Question 3

Things that are introduced from outside the body to fix or
replace a function are _________?

Answer 3

Exogenous

Question 4

__________ is the branch of pharmacology concerned with the effects of drugs and
the mechanism of their action.

Answer 4

Pharmacodynamics

Question 5

________ is the ability to bind to cell receptors

Answer 5

Affinity

Question 6

____________ is the ability to stimulate cell receptors to produce action within the cell

Answer 6

Efficacy

Question 7

_______________ is any compound that binds to specific cell receptors and produces a biological effect by stimulating these receptors.

Answer 7

Agonist

Question 8

_________ is an agent that prevents natural substances from
stimulating receptors.

Answer 8

Antagonist

Question 9

_________ Two drugs combined is greater than the effect expected if the individual effects of the two drugs independently were added together.

Answer 9

Synergism

Question 10

___________ one drug that has no effect itself enhances the effect of a second drug.

Answer 10

Potentiation

Question 11

__________ The result of neither drug giving the desired therapeutic effects.

Answer 11

Antagonism

Question 12

____________ occur when the response elicited by the combined drugs equal to the combined response of the individual drug

Answer 12

Additivity

Question 13

____________ the process in which two drugs interaction change the chemical properties of the drug

Answer 13

Drug Incompatibilities

Question 14

____________ is the physiological reactions of the body to the drug. Observable and measurable

Answer 14

Drug Effect

Question 15

(2) categories of drug effects are:

Answer 15

1. Pharmacologic (what we want it to do)
2. Non-Pharmacologic (what we don’t want it to do)

Question 16

__________ is the drug effect is limited to the site of administration and that tissue surrounding it

Answer 16

Local effect

Question 17

____________ means the drug can act and produce effect throughout the
body

Answer 17

Systemic effect

Question 18

The main effect for which it was prescribed is referred to as _____________?

Answer 18

Therapeutic effect

Question 19

____________ The effect that results from serum levels of a drug
rising above the therapeutic level

Answer 19

Toxic effect

Question 20

_______________ The expected effect that occurs as a result of a drug building up inside the body instead of being metabolized and eliminated

• Accumulation can lead to drug toxicity and/or
  over-production of the drug action.

Answer 20

Cumulative effects

Question 21

______________ is an unexpected action that is specific to an individual, may be due to an individual’s genetic make-up.

Answer 21

Idiosyncratic reaction

Question 22

_____________ is when the drug crosses placenta barrier and causes congenital abnormality or birth defect

Answer 22

Teratogenic

Question 23

The body becomes so accustomed to a drug that the body cannot
function normally without the drug – cells cannot function without
the drug describes _____________________.

Answer 23

Physical drug dependence

Question 24

produces a desire (not a compulsion) to continue taking drugs for
the sense of improved well-being is _____________.

Answer 24

Psychological dependence