Week 2 Flashcards

1
Q

The hypodermis is made of what tissues ?

A

Adipose (fat) tissues

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2
Q

Keratinocytes are continually dividing with the stem cells in what layer of the epidermis ?

A

Basal

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3
Q

If it say you have skin damage in the superficial layer what layer of skin is this?

A

Epidermis

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4
Q

If u say u have partial thickness damage to the skin what layer of skin is this ?

A

Into the dermis

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5
Q

If u say u have full thickness damage to the skin what layer of skin is this ?

A

Hypodermis/fascia/ deep tissue

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6
Q

what is the most common cellular damage thing to happen to cells?

A

Ischaemia

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7
Q
A
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8
Q

how do you remove free radicals from cells

A

antioxidants

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9
Q

why dose reperfusion lead to tissue death?

A

sudden influx of oxygen, leads to excess free radical formation
Increase intracellular calcium
either may cause cell damage, inflammation related cell death or apoptosis(programmed cell death)

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10
Q

what dose free radical cells damage ?

A

damage lipids/proteins and DNA

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11
Q

Coagulation necrosis

A

A type of cell death that occurs when blood flow to the cells stops or slows.(inschemia)

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12
Q

Liquefactive necrosis

A

partial or complete dissolution of dead tissue and transformation into a liquid, viscous mass.

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13
Q

Caseous necrosis

A

is a type of cell death that causes tissues to become “cheese-like” in appearance that from the lungs

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14
Q

Gangrene

A

death of body tissue due to a lack of blood flow or a serious bacterial infection.

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15
Q

Thombosis

A

is a blood clot within blood vessels that limits the flow of blood.

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16
Q

Fibroblast

A

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen,[1] produces the structural framework

17
Q

is a procedure for treating a wound in the skin. It involves thoroughly cleaning the wound and removing all hyperkeratotic (thickened skin or callus), infected, and nonviable (necrotic or dead) tissue, foreign debris, and residual material from dressings.

A

Debridement

18
Q

Granulated tissue

A

Granulation tissue is vascularized tissue that forms as chronic inflammation evolves. The new capillaries make the tissue appear pink and granular

19
Q

Epithelialisation

A

Is the formation of epithelium over a denuded surface ( last stage of wound healing)

20
Q

first intention of wound healing

A

Healing by first intention or Primary intention healing happens when the wound edges are approximated e.g. by sutures, staples or glue.

21
Q

Granulation

A

the development of new tissue and blood vessels in a wound during the healing process

22
Q

Secondary Wound healing.

A

Secondary intention healing means a wound will be left open (rather than being stitched together) and left to heal by itself, filling in and closing up naturally

23
Q

keloid

A

A raised scar after an injury has healed.

24
Q

Slough

A

Yellow/white material in the wound bed , its usually wet but can be dry

25
Q

Necrosis

A

Death of cells due to disease, injury or failure of blood supply or mass cell damage

26
Q

what is the most common type of necrosis?
and what is it a result from ?

A

coagulative necrosis and Ischaemia

27
Q

complications in wound healing what are the 4

A
  1. hypergranulation
  2. hypertrophic and keloid scars ( inflammation ?)
  3. sloughing and necrosis(dead tissue in wound site)
  4. fistula formation (inapproiate connection to organs
28
Q

why does many wound complications happen in tissues?

A

excessive collagen formation and possibly due to excess inflammation