Week 1 Review Qs Flashcards
Which of the following muscle is involved in abduction?
A. Pectoralis Major
B. Deltoid
C. Serratus Anterior
D. Latissimus Dorsi
B. Deltoid
Which muscle is innervated by the lower subscapular nerve? (Repeated)
A. Teres Minor
B. Rhomboid Major
C. Teres Major
D. Rhomboid Major
C. Teres Major
Paralysis of which muscle would result in loss of retraction of the scapula? (Repeated)
A. Subscapularis
B. Pectoralis Minor
C. Levator Scapula
D. Rhomboid Major
D. Rhomboid Major
Which muscle initiates shoulder abduction? (Repeated)
A. Deltoid
B. Supraspinatus
C. Anconeus
D. Latissimus Dorsi
B. Supraspinatus
Which muscle is responsible for swinging the upper limb anteriorly and posteriorly when walking? (Repeated)
A. Deltoid
B. Anconeus
C. Trapezius
D. Coracobrachialis
A. Deltoid
Which of the following pairs are the major lateral rotators of the arm?
A. Pectoralis Major and Minor
B. Teres Major and Minor
C. Infraspinatous and teres minor
D. Supraspinatous and Pectoralis Minor
C. Infraspinatous and teres minor
What is the function of the subscapular muscle? (repeated)
A. Abductions
B. Medial Rotation
C. Suppination
D. Extension
B. Medial Rotation
Which two muscles are innervated by the axillary nerve?
A. Teres Minor
B. Trapezius
C. Supraspinatus
D. Deltoid
A & D Teres Minor and Deltoid
Which diseases is characterized by a mosaic pattern of bone and occurs in the elderly?
Paget’s disease
Which of the following is a feature of dermatomyositis?
A. Variation in Fiber size with large rounded fiebrs
B. Muscle replcaement by fat and fibrous tissue
C. Perifascicular atrophy
D. Marked Endomysial fibrosis
C. Perifascicular atrophy
Non-union of a spirally fractured bone would result in what?
Pseudoarthrosis
What is a feature of fast muscle fibers? (repeated)
A. Few Mitochondira
B. High Oxidative capacity
C. Smallest Diameter
D. Used in Endurance activites
A. Few Mitochondria
Which of the following generates maximal force of contraction [or: when does maximum muscle tension develop]?
100% overlap between actin and myosin
Which of the following is responsible for the ATP dependent power stroke?
Myosin head
Which of the following functions as an immediate source of ATP in muscles?
Creatine phosphate
What enzyme generates an ATP molecule from 2 ADP molecules?
Adenylate kinase
Someone who works with cattle and develops sacroiliitis. What is the causative organism?
Brucella abortus
A man in Ohio presents with a bone infection. Biopsy shows intracellular budding yeast. What is the cause?
Histoplasmosis
Which of the following causes mild self-limiting arhtirtis [desert rheumatism]?
Coccidiomycosis
A neutropenic patient suffers from an infection. Biopsy shows septate hyphae branched at acute angles. What is the cause?
Aspergillosis
Aneutropenic patient with a catheter suffers from an infection at the catheter site. Biopsy shows nonseptate hyphae. What is the cause?
Mucoralis
ATP binding to myosin head results in?
Detachment of myosin head from f-actin
A storage form of ATP?
Creatinine-phosphate
Substrate of adenylate kinase?
ADP
Which one of the following ligaments prevents upward dislocation?
Coracoacromial ligament
Responsible for bone resorption during fracture healing?
Osteoclast
What happens metabolically immediately after calcium release from sarcoplasmic reticulum?
Glycogenolysis and glycolysis
What causes fatigue in fast muscle fibers?
Glycogen depletion
What is responsible for the opening of voltage gated calcium channels?
Change in the molecular structure of the channel
A boy fell on an outstretched hand and had a distal forearm fracture. A cast is applied and an x-ray is dome after two weeks shows a soft callus. What histologic change would you find?
A. Woven bone
B. Laminar bone
C. Granulation tissue
D. Hematoma
E. Fibrocartilage
E. Fibrocartilage
An elderly man has alkaline phosphate in his serum. A bone biopsy from his vertebrae showed a mosaic pattern. What is the mechanism?
Paget’s disease
What is the impingement test used for?
Supraspinatous
Fibeocartilage prone to injury in shoulder dislocation?
Glenoid labrum
What is a characteristic of fast twitch muscle?
Few mitochondria
Injury to spinal accessory nerve lead to paralysis of which muscle?
Trapezius
injury to long thoracic nerve affects which muscle?
Serratus anterior
Two diagrams showing the decrease in Ceratinine phosphate and glycogen levels with time. What is the main physiological consequence of this?
Muscle fatigue
What is the preferred pathway for energy production during short strenuous workout and why?
A. Glycogen → glucose → glycolysis, because it passes the slow step of hexokinase
B. Blood glucose → glucose → glycolysis, because insulin initiates glucose uptake
C. Free fatty acids → B oxidation, because it gives more energy per molecule
A. Glycogen → glucose → glycolysis, because it passes the slow step of hexokinase
Activity of which of the following enzymes will increase during short strenuous workout?
Lactic acid dehydrogenase
In bone fracture, which of the following proteins/factors increase chondrocyte proliferation?
A. Parathyroid hormone
B. Metalloprotease
C. Bone morphogenic protein
D. PDGF
E. VEGF
C. Bone morphogenic protein
What are the chief lateral abductors of the arm?
A. Infraspinatous and teres major
B. Supraspinatous and infraspinatous
C. Teres major and subscapularis
D. Supraspinatous and deltoid
A. Infraspinatous and teres major
A fractured hip of an elderly patient is most known as fracture of the?
A. Ilium
B. Neck of femur
C. Acetabulum
B. Neck of femur
A 17 year old man fractured his left femur in a car accident, a year later an x-ray was done for check-up and no traces of the fracture were there, what final event lead to the x-ray finding?
A. Bone remodelling
B. Callus formation
C. Hematoma
A. Bone remodelling
A 48 year old female sustained a left humerus fracture, and it was provided that she underwent breast cancer surgery 2 years ago. PET examination showed red hot spots in her skeleton and lungs. What is the most likely finding?
A. Pathological fracture
B. Non-union
C. Soft callus
D. Hard callus
E. Greenstick
A. Pathological fracture
What is the effect of smoking on bone healing?
A. Vasoconstriction which diminishes blood flow to the fracture area
B. Produce some cytokines
A. Vasoconstriction which diminishes blood flow to the fracture area
What is the initial management for open fracture of humerus?
A. Immediate IV antibiotics
B. Cast
C. Sterile dressing
A. Immediate IV antibiotics
A child with a lymphoma experienced an infection related to the catheter, a biopsy showed branched septate hyphae with acute angle, what is the cause?
Aspergillosis
Intravenous drug user with arthritis, synovial fluid showed yeast cell pseudohyphae, what is the causative organism?
Candida albicans
What will happen if we blocked the Na channels?
A. Hyperpolarization
B. We will not be able to generate action potential
B. We will not be able to generate action potential
A 35 year old woman presented with bright red rash on her face and joint pain, synovial fluid analysis showed viral DNA
A. Parvovirus B19
B. Rubella virus
A. Parvovirus B19
A patient with multiple old and new fractures, absence of bone architecture, and decrease bone marrow space. What is the diagnosis?
A. Osteopetrosis
B. Osteogenesis imperfecta
A. Osteopetrosis
What is produced by pentose phosphate pathway?
A. PRPP
B. IMP
C. Ribose-5-phosphate
C. Ribose-5-phosphate
Which rotator cuff muscle is easily impinged?
A. Supraspinatus
B. Subscapularis
A. Supraspinatus
A 54 year old man presented with increased levels of alkaline phosphate, the bone showed mosaic pattern? What is the mechanism of this disease?
Osteoclast dysfunction
A diabetic patient underwent surgery 2 weeks ago. Now he presents with fungal infection with necrosis, non-septate hypha, what is the most likely causative pathogen?
A. Mucor
B. Coccidiomycosis
A. Mucor
A boy in car traffic accident got a fungal infection with budding pseudohyphae?
Candida Albicans
What is responsible for pain occurring between 60-120 degrees of abduction in painful arc?
A. Impingement syndrome
B. Osteoarthritis of shoulder
C. Biceps tendinitis
D. Subscapularis tendinitis
A. Impingement syndrome
What transports calcium after end of stimulation?
SERCA
What is responsible for conduction of action potential?
A. Na channel
B. Ach receptors
C. Ryanodine receptors
D. DHPR
A. Na channel
Someone with fracture came after 2 weeks and there was swelling and no calcification on x-ray, in which phase is he going through?
A. Hard callus
B. Soft callus
C. Hematoma
B. Soft callus
Which mechanism ensures uni-directional propagation of action potential?
A. Temporary inactivation of Na/K ATPase pump
B. Simultaneous closure of activation and inactivation gates of Na channels
C. Depolarization after action potential passed the axon segment
D. Hyperpolarization during the refractory peroid
D. Hyperpolarization during the refractory period
What causes increase in K+ inside cell?
Na/K+ ATPase
Which of the following generates maximal force of contraction?
100% overlap between actin and myosin
What will happen after powerstroke
ATP binds