Week 1 - Exam 1 Flashcards
definition of pharmacology
study of actions of drugs on living systems
definition of a drug
‘A substance used as a medication or in the preparation of medication’
definition of clinical pharmacology
the application of pharmacology principles to patients
definition of pharmacy
the study of the preparation of drugs
definition of toxicology
the study of poisons and their treatments
what does pharmacokinetics entail
Absorption, Distribution, Metabolism, Excretion
5 pillars of pharmacology
drug, pharmacokinetics, pharmacodynamics, pharmacotherapeutics, drug toxicity
3 main types of drug sources
natural, semisynthetic, synthetic
4 types of natural drugs
plant, animal, fungi, bacteria
7 active compounds in plants (All Good Rossies Get To Finish Victoriously)
alkaloids, glycosides, resins, gums, tannins, fixed oils, volatile oils
alkaloid characteristics
basic nitrogenous substances, insoluble in water, end in -ine
glycosides are
sugars
resin characteristic
polymerization of volatile oils
gums characteristics
polysaccharides, trees
tannins characteristics
non-nitrogenous, astringent effect
fixed oils characteristics
stable, won’t evaporate
volatile oils characteristic
will evaporate
3 types of animal sources
blood, plasma, hormones
drugs from bacteria/fungi
antibiotics
definition of dose
amount of drug given to achieve a certain effect
definition of dosage
amount of drug per unit body weight i.e.: mg/kg, etc.
definition of concentration
amount of drug per unit of volume from the stock supply of medication aka dosage form or formulation i.e.: mg/mL, 100mg tab, 25mg cap, etc.
4 categories of drug products
OTC, prescription, biologics (vax), controlled
OTC drugs don’t need
a prescription
prescription drugs regulated by
the FDA, NADA
biologics regulated by
the USDA
FDA stands for _____; function
Food and Drug Administration, drug approval and safety
DEA stands for _____; function
Drug Enforcement Administration, high abuse potential i.e.: controlled
NDC stands for _____; function
National Drug Code, 10 digits, DEA
NADA stands for _____; function
New Animal Drug Application, FDA
controlled drugs regulated by _______; how many classes
DEA, 5 classes/schedules based on potential for abuse (lower class = higher potential)
definition of a prescription
An order to a pharmacist written by a licensed medical practitioner, legally recognized document
required text for a prescription includes:
Name, address, and phone number of hospital, Name of patient (species is also helpful), Patient’s body weight, Name and address of patient’s owner (client), Date prescription is written, Number of refills permitted, Clinician’s DEA registration number must be provided for controlled drugs, Withdrawal time for food animals, Name and strength of medication, Quantity to be dispensed, Directions for Use: include amount of medication, route of administration, frequency of treatment
schedule II drugs restrictions
written, 0 refills, 30 day supply
schedule III, IV, V restrictions
usually faxed, can’t be called in, up to 5 refills within 6 months
AMDUCA stands for ______; function
Animal Medicinal Drug Use Clarification Act; extra label use
FARAD stands for ______; function
Food Animal Residue Avoidance Databank; food animal drug withdrawal times
4 types of dosage forms of drugs
solid, liquid, semisolid, gases/vapors
local routes of administration
skin, nasal, ocular, urinary tract, vaginal, rectal, mammary, (sub)lingual, GI mucosa, otic, intraspinal/synovial/medullary
systemic routes of administration
per os, enteral, perenteral
perenteral routes of administration
IV, IM, SQ, IP, TM, IB, IO, gases, vapors, endotracheal
definition of a powder
mixture of drugs packaged in packets or sachets
definition of a tablet
active drug combined with a binder and excipient; can cut
definition of a enteric-coated tablet
irritants or ones destroyed by gastric acid are coated and dissolve in the SI
definition of a pill
mixture of drugs and a sticky binder glazed sugar coating; can’t cut
definition of a capsule
container made of mixture of gelatin and glycerin to hold powdered drugs (powder and liquid)
definition of a bolus
large and cylindrical shape for horses and cows
definition of a mixture
aq soln or suspension for oral administration
definition of a pessary
conical solid preparation for intravaginal use in humans
definition of a suppository
conical solid preparation given intrarectally for systemic effects in humans, melts and releases ingredients
definition of a paste
semisolid preparation for external or internal use
definition of a electuary
semisolid preparation applied to the back of the tongue, systemic (large animal med)
definition of a tincture
alcoholic liquid nonvolatile substance external/internal use
definition of a spirit
alcoholic liquid volatile substance
definition of a suspension
aqueous suspension of solids and contains dispersing agent “shake well before use”
definition of a syrup
soln of medicinal agents, flavoring, coloring, 85% sucrose soln
definition of an elixir
hydroalcoholic soln sweetened and flavored
definition of an emulsion
oily substance in aqueous medium
definition of an extract
pass solvent over dried plant material then evaporate solvent
definition of infusion
cold or warm water for extraction
definition of decoction
boiling water for extraction
definition of injection
sterile solns in aq vehicle. heat sterilized or filtered.
definition of repository forms
slow release
definition of a liniment
liquid or semisolid applied on skin with friction
definition of a lotion
soln soothing applied on skin
definition of a ointment
semisolid greasy dissolved on skin
definition of a cream
water-oil emulsion, water evaporate after application
definition of a dusting powder
mix of drugs in powder for external use
definition of an aerosol
solvent and packaged under pressure with a propellant
a.c. stands for
before meals
p.c. stands for
after meals
c stands for
with
s stands for
without
aq stands for
water
et stands for
and
noct stands for
night
definition of a compounded medication
combining or altering ingredients
example of Class I drug
heroin, LSD
example of Class II drug
morphine
example of Class III drug
anabolic steroids
example of Class IV drug
butorphanol & diazepam
example of Class V drug
buprenorphine