Redistribution of Drugs - Exam 3 Flashcards
1
Q
definition of the redistribution of drugs
A
the movement of drugs from the tissues back to the bloodstream
2
Q
drugs don’t only go to the intended site of action, they can also
A
be distributed to other tissues
3
Q
drugs usually have to return to the bloodstream to get to the liver/kidney for
A
metabolism/excretion
4
Q
example of redistribution
A
thiopental: highly lipophilic, site of action is brain, some stored in fat, excreted slowly, redistributed to fat until fully saturated, then has nowhere to go so will redistribute back to the bloodstream, back to the brain