Week 1 Flashcards
The function of each cell type
Osteoblasts are immature bone cells that form bone.
Osteocytes are mature bone cells that maintain or nurture bone.
Osteoclasts remodel bone
What types of glycosaminoglycans dominate in bone
Chondroitin sulfate, keratin sulfate and hyaluronic acid
What is wolff’s law as it pertains to bone
Living tissue will respond to stressors; bone is formed or absorbed in response to stress
What is osteology
The study of bone
What are the bone cells embedded in?
An amorphous Matrix consisting of ground substance, protein fibers and various minerals
What is the primary constituent of ground substance?
Glycosaminoglycans
What is the principle type of protein fiber in bone? Cartilage?
Bone=type 1
Cartilage=type 2
What is the primary constituent of bone mineral
Calcium, phosphate, citrate, and carbonate ions
What is the most frequently described deposit in bone?
Hydroxyapatite
Bone is also a repository for what additional ions?
Sodium, magnesium, fluoride, Lead, strontium, and radium
What are the three responses of bone that allow it to be described as living?
It has the ability to heal, to remodel under stressors and to age
What is bone the embryological derivative of?
Mesenchyme or cartilage
What is the name of the pattern of ossification in Mesenchyme?
Intramembranous ossification
What is the timing for the appearance of intramembranous ossification?
From the second to third month in utero
What is the name given to the pattern of ossification in cartilage?
Endochondral ossification
What is the timing of the appearance of ossification in cartilage?
From the second to fifth month in utero