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Physiology 1 > Week 1 > Flashcards

Week 1 Flashcards

1
Q

Na+ E.C

A

135 - 147 mM

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2
Q

K+ E.C

A

3.5 - 5.0 mM

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3
Q

Ca2+ E.C (Total, Blood plasma)

A

2.1 - 2.8 mM

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4
Q

Ca2+ E.C (Free)

A

1.1 - 1.4 mM

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5
Q

Cl- E.C

A

95 - 105 mM

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6
Q

HCO3- E.C

A

22 - 28 mM

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7
Q

Osmolarity E.C

A

290 mOsm

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8
Q

pH

A

7.38 - 7.42

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9
Q

How do we monitor deviations from set point of K+ E.C conc.?

A

Glomerulosa cells of Adrenal Glands

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10
Q

Elevated E.C K+, how to decrease?

A

Aldosteron

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11
Q

What Phospholipid is used for Signal transduction?

A

Phosphatidylinositol

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12
Q

Outer Phospholipids

A

Phosphatidylcholine
Sphingomyelin

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13
Q

Inner Phospholipids

A

Phosphatidylinositol
Phosphatidylserine
Phosphatidylethanolamin

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14
Q

What Glycolipid is used as a protein anchor?

A

(GPI) Glycosylphosphatidylinositol

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15
Q

Types of Plasma membrane Proteins

A

Integral Mem. P
Lipid-Anchored P
Peripheral P

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16
Q

Integral proteins examples

A

Transmembrane Proteins

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17
Q

Lipid-Anchored proteins examples

A

GPI-bound Proteins
Lipid modification (Palmitoilation)

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18
Q

Total Body Water

A

0.6 x body weight
42L (70Kg)

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19
Q

Extracellular Fluid

A

0.2 x Body weight
14L (70Kg)

20
Q

Intracellular Fluid

A

0.4 x body weight
28L (70Kg)

21
Q

Interstitial Fluid

A

3/4 of Extracellular Fluid
10.5L (70Kg)

22
Q

Plasma

A

1/4 of Extracellular Fluid
3.5L (70Kg)

23
Q

Na+ I.C

A

10 - 15 mM

24
Q

K+ I.C

A

120 - 150 mM

25
Q

Ca2+ I.C

A

100 nM (free)

26
Q

Cl- I.C

A

20 - 30 mM

27
Q

HCO3- I.C

A

12 - 16 mM

28
Q

Osmolarity I.C

29
Q

pH I.C

30
Q

Fick’s First Law of Diffusion

A

J = ( D A / X ) * C
Rate = (d.coeff * area/distance) * Conc. difference

31
Q

Measurement of Total Fluid Compartment

32
Q

Measurement of Extracellular Fluid

33
Q

Measurement of Blood Plasma

A

Evans-blue (protein-bound dye)
Protein

34
Q

Properties of Carriers (Enzymes)

A

Passive / Active
Slow
Saturation

35
Q

Properties of Channels (Gates)

A

Passive
Fast
Can NOT be saturated

36
Q

GLUT-1

37
Q

GLUT-2

A

Liver
Pancrease (B-Cells)
Small intestine

38
Q

GLUT-3

A

Brain / Neurons
Sperm

39
Q

GLUT-4

A

Skeletal Muscle
Adipose tissue
Cardiac Muscle

40
Q

Which cells are the Glucose sensitive cells?

41
Q

Van’t Hoff’s Law on Osmotic Pressure

A

pi = RTnc
osm.p = 8.31 * temp * n * conc.

42
Q

Negative Feedback

A

Homeostasis

43
Q

Positive feedback

A

Increased activation
Ovulation
Gating of ion channel

44
Q

Servo-Control reg

A

Fever
Exercise
(Set point has been changed)

45
Q

Feed-forward control

A

Thermoreg
Osmoreg

Physiology 1 (12 decks)

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