W27-L5: Fungi Flashcards
1
Q
What is the classification of fungi?
A
- unicellular (yeasts) which are anaerobes
- filamentous (moulds) which are aerobes
- dimorphic
2
Q
What are most of the pathogenic fungi?
A
Saprophytes
3
Q
What are dermatophytes?
A
fungi that don’t invade deeply, cause tinea
4
Q
What is a mycetoma?
A
infection of subcutaneous skin of the foot
5
Q
What are some examples of opportunistic mycoses?
A
- candidiasis
- cyrptococcosis
6
Q
What is a mycosis?
A
fungal infection
7
Q
Why is cyrptococcal meningitis important?
A
Is an AIDS defining infection
8
Q
How do you diagnose fungal infection?
A
- Microscopy: Fungi, Hyphae
- Culture
- Antigen detection: latex agglutination
- PCR
- Mass spec
9
Q
What are targets of anti-fungals?
A
- ergosterol in cytoplasmic membrane
- nucleic acids
10
Q
<p>What is treatment for systemic fungal infections?</p>
A
<p>Variable but all involve
</p>
11
Q
What is the treatment for dermatophytosis?
A
Topical or oral to reduce fungal load