W27-L5: Fungi Flashcards

1
Q

What is the classification of fungi?

A
  • unicellular (yeasts) which are anaerobes
  • filamentous (moulds) which are aerobes
  • dimorphic
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2
Q

What are most of the pathogenic fungi?

A

Saprophytes

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3
Q

What are dermatophytes?

A

fungi that don’t invade deeply, cause tinea

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4
Q

What is a mycetoma?

A

infection of subcutaneous skin of the foot

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5
Q

What are some examples of opportunistic mycoses?

A
  • candidiasis

- cyrptococcosis

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6
Q

What is a mycosis?

A

fungal infection

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7
Q

Why is cyrptococcal meningitis important?

A

Is an AIDS defining infection

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8
Q

How do you diagnose fungal infection?

A
  • Microscopy: Fungi, Hyphae
  • Culture
  • Antigen detection: latex agglutination
  • PCR
  • Mass spec
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9
Q

What are targets of anti-fungals?

A
  • ergosterol in cytoplasmic membrane

- nucleic acids

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10
Q

<p>What is treatment for systemic fungal infections?</p>

A

<p>Variable but all involve
</p>

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11
Q

What is the treatment for dermatophytosis?

A

Topical or oral to reduce fungal load

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