Vocab Flashcards
absorbance (A)
a logarithmic expression of the amount of light absorbed by a substance containing colored molecules; optical density (O.D.)
accessioning
the process by which specimens are logged in, labeled, and assigned a specimen identification code
accreditation
a voluntary process in which an independent agency grants recognition to institutions or programs that meet or exceed established standards of quality
acidosis
a condition in which blood pH falls below 7.35
acquired immunodeficiency syndrome (AIDS)
a form of severe immunodeficiency caused by infection with the human immunodeficiency virus (HIV)
activated clotting time (ACT)
a test that assesses the effect of heparin on the ability of blood to clot
activated partial thromboplastin time (APTT)
the time required for a fibrin clot to form when CaCl2 is added to citrated plasma that has been activated with partial thromboplastin reagent
acute phase proteins
proteins that increase rapidly in plasma during acute infection, during inflammation, or following tissue injury
adhesion
the act of two parts of surfaces sticking together
aerobic
requiring oxygen for growth
aerosol
liquid in the form of a very fine mist
agar
a seaweed derivative used to solidify microbiological media
agglutination
the clumping or aggregation of particulate antigens result from reaction with specific antibody.
agglutination inhibition
interference with, or prevention of, agglutination
aggregate
the total substances making up a mass; a cluster or slump of particles
aggregation
the collecting of separate objects into one mass
agroterrorism
acts of terrorism involving threats to agricultural products, including food animals and crops
Airborne Precautions
a Centers for Disease Control and Prevention (CDC) isolation category designed to prevent transmission of infectious diseases, such as measles, that are spread by the airborne route
alanine aminotransferase (ALT)
an enzyme present in high concentration in the liver and measured to assess liver function; formerly called SGPT
albumin
the most abundant protein in normal plasma; a homogeneous group of plasma proteins that are made in the liver and help maintain osmotic balance
albumins
the most abundant protein in normal plasma; a homogeneous group of plasma proteins that are made in the liver and help maintain osmotic balance
alimentary tract
the digestive tube from the mouth to the anus
alkaline phosphate (ALP or AP)
an enzyme widely distributed in the body, especially in the liver and bone
alkalosis
a condition in which blood pH rises above 7.45
allele
one of two (or more) forms of a gene responsible for genetic variation
allergy
a condition resulting from an exaggerated immune response; hypersensitivity
alpha cell
a type of cell in the islets of Langerhans that makes and secretes glucagon
ameba (pl. amebae)
a single-celled eukaryotic organism lacking a definite shape and moving by means of pseudopodia; also spelled amoeba (pl. amoebae)
American Association of Blood Banks (AABB)
international association that sets blood bank standards, accredits blood banks, and promotes high standards of performance in the practice of transfusion medicine
American Association of Medical Assistants (AAMA)
professional society and credentialing agency for medical assistants
American Medical Technologists (AMT)
professional society and credentialing agency for several categories of medical laboratory personnel
American Society for Clinical Laboratory Science (ASCLS)
professional society for clinical/medical laboratory personnel
American Society for Clinical Pathology (ASCP)
professional society for clinical/medical laboratory personnel and allied health personnel
American Society for Phlebotomy Technicians (ASPT)
professional society and credentialing agency for phlebotomists, as well as credentialing agency for specialty areas such as point-of-care technician
amorphous
without definite shape
amorphous phosphates
granular crystals without uniform shape that can form in alkaline urine, give urine sediment a whitish appearance after contrifugation, and appear clear microscopically
amorphous urates
granular crystals without uniform shape that can
form in acid urine, can give urine sediment a pink appearance after
centrifugation and appear yellowish microscopically
amperometry
the technology that uses electrodes and electrode potential to measure electron generation
anaerobic
growing in the absence of oxygen
analyte
a chemical substance that is the subject of chemical analysis
anamnestic response
rapid increase in blood immunoglobulins following a second exposure to an antigen; also called booster response or secondary response
anemia
a condition in which the red blood cell count or hemoglobin level is below normal; a condition resulting in decreased oxygen-carrying capacity of the blood
anion
a negatively charged ion
anion gap
a mathematical calculation of the difference between the cations and anions measured in the electrolyte assay
anisocytosis
marked variation in the sizes of erythrocytes
anopheles
he genus of mosquito that is the definitive host for the human malaria parasites (genus Plasmodium) and that is capable of transmitting the organism to humans
antibiotic susceptibility testing
determining the susceptibility of bacteria to specific antibiotics
antibody (Ab)
protein that is induced by, and reacts specifically with, a foreign substance (antigen); immunoglobulin
anticoagulant
a chemical or substance that prevents blood coagulation
antigen (Ag)
foreign substance that induces an immune response by causing production of antibodies and/or sensitized lymphocytes that react specifically with that substance; immunogen
anti-human globulin test
a sensitive test that uses a commercial anti-human globulin reagent to detect human globulin coated on red blood cells; antiglobulin test; Coombs’ test
antiseptic
a chemical used on living tissues to control the growth of infectious agents
antiserum
serum that contains antibodies
anuria
absence of urine production; failure of kidney function and suppression of urine production
aperture
an opening
apheresis
the process of removing a specific component, such as platelets, from donor blood, and returning the remaining blood components to donor circulation
APIC
Association for Professionals in Infection Control and Epidemiology, an organization working across a spectrum of professionals, organizations, and institutions to prevent healthcare-associated infections
arteriole
a small branch of an artery leading to a capillary
arteriosclerosis
abnormal thickening and hardening of the arterial walls, causing loss of elasticity and impaired blood circulation
artery
a blood vessel that carries oxygenated blood from the heart to the tissues
arthritis
inflammation of the joints, due to several causes
arthropod
a member of the phylum Arthropoda, which includes crustaceans, insects, and arachnids
ASCP Board of Certification (ASCP BOC)
a separate body within the ASCP organizational structure, formed in 2009 by merging NCA with the ASCP BOR and providing certification for medical laboratory personnel
aseptic technique
work practices used to prevent contamination when working with microorganisms
asparate aminotransferase (AST)
an enzyme present in many tissues, including cardiac, muscle, and liver, that is measured to assess liver function; formerly called SGOT
artherosclerosis
a form of arteriosclerosis in which lipids, calcium, cholesterol, and other substances deposit on the inner walls of the arteries
atrial
of or relating to a body cavity
atypical lymphocyte
lymphocyte, usually large, that occurs in response to viral infections and is common in infectious mononucleosis; reactive lymphocyte
autoantibody
an antibody directed against self (one’s own tissues)
autoclave
an instrument that uses pressurized steam for sterilization
autoimmune disease
disease caused when the immune response is directed at one’s own tissues (self-antigens)
average
the sum of a set of values divided by the number of values in the set; the mean
avian influenza
an infection of birds with one of the influenza Aviruses; bird flu
azidemethemoglobin
a stable compound formed when azide combines with methemoglobin
azurophilic
a term used to describe the reddish-purple staining characteristics of certain blood cells; the quality of staining with azure dyes
B lymphocyte (B cell)
the type of lymphocyte primarily responsible for the humoral immune response
babesiosis
an infection spread by tick bite and caused by protozoan parasites of the genus Babesia
bacillus
a rod-shaped bacterium
bacteriology
the study of bacteria
band cell
an immature granulocyte with a nonsegmented nucleus; a “stab cell”
basilic vein
large vein on inner side (“pinky” side) of arm
basophil
a leukocyte containing basophilic-staining granules in the cytoplasm
basophilia
abnormal increase in the number of basophils in the blood; basophilic leukocytosis; also, the affinity of cellular structures for basophilic dyes
basophilic
blue in color; having affinity for the basic stain
basophilic stippling
remnants of RNA and other basophilic nuclear material remaining inside the red blood cell after the nucleus is lost from the cell; small purple granules in red blood cells stained with Wright’s stain
Beer’s law
a mathematical relationship that demonstrates the linear relationship of concentration to absorbance and that forms the basis for spectrophotometric analysis
beta cell
a type of cell in the islets of Langerhans that makes and secretes proinsulin and insulin
bibulous paper
a special absorbent paper used to dry slides; blotting paper
bilirubin
a product formed in the liver from the breakdown of hemoglobin
binocular
having two oculars or eyepieces
biohazard
risk or hazard to health or the environment from biological agents
biological safety cabinet
a special work cabinet that provides protection to the worker while working with infectious microorganisms
biosafety level 4 (BSL-4)
a designation requiring the use of a combination of work practices, equipment, and facilities to prevent exposure of individuals or the environment to pathogens that can be transmitted by aerosol and that pose a high risk for life-threatening disease for which treatment or vaccine is not generally available
birefringence
he characteristic of double refraction; the characteristic of being able to split a beam of polarized light into two light beams
blast cell
an immature blood cell normally found only in the bone marrow
blind sample
an assayed sample that is provided as an unknown to laboratories participating in proficiency testing programs
blood bank
clinical laboratory department where blood components are tested and stored until needed for transfusion; immunohematology department; transfusion services; also the refrigerated unit used for storing blood components
blood group antibody
a protein (immunoglobulin) that reacts specifically with a blood group antigen
blood group antigen
a substance or structure on the red blood cell membrane that stimulates antibody formation and reacts with that antibody
blood urea nitrogen (BUN)
a test measuring urea nitrogen in blood
Bloodeborne Pathogens (BBP)
pathogens that can be present in human blood (and blood-contaminated body fluids)
Bloodeborne Pathogens (BBP) Standard
OSHA guidelines for preventing occupational exposure to pathogens present in human blood and body fluids, including, but not limited to, HIV and hepatitis B virus (HBV); final OSHA standard of December6, 1991, effective March6, 1992
borosilicate glass
nonreactive glass with high thermal resistance commonly used to make high-quality labware
botulinum intoxication
a condition in which body tissues are affected by the botulinum toxin
botulinum toxin
a neurotoxin produced by Clostridium botulinum
bovine spongiform encephalopathy (BSE)
a fatal, neurological disease of cattle caused by an unconventional transmissible agent called a prion; commonly called “mad cow disease”
Bowman’s capsule
the portion of the nephron that receives the glomerular filtrate
bradyzoite
a slowly multiplying form of coccidian parasite found within tissue cysts and typical of chronic infection with Toxoplasma gondii
B-type natriuretic peptide (BNP)
a peptide hormone released primarily from the ventricles of the heart and used as a marker for cardiac function
buffer
a substance that lessens change in the pH of a solution when acid or base (alkali) is added
buffy coat
a light-colored layer of white blood cells and platelets that
forms on top of the red blood cell layer when a sample of blood is centrifuged or allowed to stand undisturbed
calibration
the process of checking, standardizing, or adjusting a method or instrument so that it yields accurate results
Candida albicans
yeast that causes vaginitis and other infections, especially following antibiotic therapy
capillary
a minute blood vessel that connects the smallest arteries to the smallest veins and serves as an oxygen exchange vessel
capillary action
the action by which a fluid enters a tube because of the attraction between the fluid and the tube
capillary tube
a slender glass or plastic tube used for laboratory procedures
carcinogen
a substance with the potential to produce cancer in humans or animals
cardiopulmonary circulation
the system of blood vessels that circulates blood from the heart to the lungs and back to the heart
cardiovascular disease (CVD)
disease of the heart and blood vessels resulting from a variety of causes
carrier
an individual who harbors an organism and is capable of spreading the organism to others, but has no symptoms or signs of disease
cast
in urinalysis, a protein matrix formed in the kidney tubules and washed out into the urine
cation
a positively charged ion
catalase test
a test to differentiate between Streptococcus and Staphylococcus species
caustic
a chemical substance having the ability to burn or destroy
tissue
cell-diluting fluid
a solution used to dilute blood for cell counts
cell-mediated immunity
immunity provided by T lymphocytes and cytokines
cellular respiration
the series of cellular metabolic processes in which organic substances are oxidized and energy in the form of ATP is released
Celsius (C) scale
temperature scale having the freezing point of water at 0°C and the boiling point at 100°C
Centers for Disease Control and Prevention (CDC)
central laboratory for the national public health system
Centers for Medicare and Medicaid Services (CMS)
the agency within the Department of Health and Human Services (DHHS) responsible for implementing CLIA ’88
centi
prefix used to indicate one-hundredth [10^(-2)] of a unit
centrifuge
an instrument with a rotor that rotates at high speeds in a closed chamber
cephalic vein
a superficial vein of the arm (thumb side) commonly used for venipuncture
cerebrospinal fluid (CSF)
the fluid surrounding the spinal cord and bathing the ventricles of the brain
cestode
tapeworm; member of the class Cestoda
chemical hygiene plan
comprehensive written safety plan detailing the proper use and storage of hazardous chemicals in the workplace
Chlamydia trachomatis
species of gram-negative intracellular bacteria that is a cause of sexually transmitted diseases (STDs)