unit 3 vocab Flashcards
Basic Hemostasis
adhesion
the act of two parts or surfaces sticking together
aggregation
/ the collecting of separate objects into one mass
arteriosclerosis
abnormal thickening and hardening of the arterial walls, causing loss of elasticity
and impaired blood circulation
atherosclerosis
a form of arteriosclerosis in which lipids, calcium, cholesterol, and other substances deposit
on the inner walls of the arteries
coagulation
/ the process of forming a fibrin clot
coagulation factors /
a group of plasma proteins (and the mineral calcium) involved in blood clotting
collagen
/ a protein connective tissue found in skin, bone, ligaments, and cartilage
Coumadin
/ an anticoagulant drug derived from coumarin that is administered orally to prevent blood clotting
or to reduce the risk of clots; a trade name for warfarin
D-dimer
/ the smallest cross-linked fibrin degradation fragment formed from the breakdown of polymerized
fibrin by plasmin
embolus (pl. emboli)
a mass (clot) of blood or foreign matter carried in the circulation
endothelium
/ the layer of epithelial cells that lines blood vessels and the serous cavities of the body
FDPs
fibrinogen or fibrin monomer degradation products formed when plasmin cleaves fibrinogen or fibrin
monomers into protein fragments; formerly called fibrin split products
fibrin
a protein formed from fibrinogen by the action of thrombin
fibrinogen
a plasma protein produced in the liver and converted to fibrin through the action of thrombin
fibrinolysis
enzymatic breakdown of a blood clot
glycoprotein
a protein molecule having a carbohydrate component
hemorrhage
/ uncontrolled bleeding
hemostasis
/ the process of stopping bleeding, which includes clot formation and dissolution
heparin
/ an anticoagulant used therapeutically to prevent thrombosis; also used as an anticoagulant in certain
laboratory procedures
inhibitor
a substance that retards or stops a process or chemical reaction
intravascular
/ within the blood vessels
ionized calcium
/ in the body, a mineral that plays an important role in hemostasis
megakaryocyte
a large bone marrow cell from which platelets are derived
plasmin
an enzyme that binds to fibrin and initiates breakdown of the fibrin clot (fibrinolysis)