Vitamin B3 (Niacin) Flashcards
1
Q
Mechanism of Action
A
- Acts as a coenzyme in oxidation-reduction rxns necessary for cell metabolism.
- Decreases production of VLDL (occurs in high doses)
- Raises HDL (no effect seen on mortality)
2
Q
Pregnancy Category
A
- Pregnancy Category A (@ RDA values)
- C (>RDA)
3
Q
Adverse Effects
A
- Intense flushing and hot flashes
- Nausea
- Diarrhea
- Excess gas
- Paresthesias
- Increased blood sugars
4
Q
Serious Adverse Effects
A
- hepatotoxicity
- gout
5
Q
Nursing considerations
A
- Instruct patient not to self-medicate
- Patient teaching about side effects
- Med hx
- Additive effects w/ other drugs
- Diabetes
- Liver disease
- Gout