Vitamin B3 (Niacin) Flashcards

1
Q

Mechanism of Action

A
  • Acts as a coenzyme in oxidation-reduction rxns necessary for cell metabolism.
  • Decreases production of VLDL (occurs in high doses)
  • Raises HDL (no effect seen on mortality)
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2
Q

Pregnancy Category

A
  • Pregnancy Category A (@ RDA values)

- C (>RDA)

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3
Q

Adverse Effects

A
  • Intense flushing and hot flashes
  • Nausea
  • Diarrhea
  • Excess gas
  • Paresthesias
  • Increased blood sugars
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4
Q

Serious Adverse Effects

A
  • hepatotoxicity

- gout

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5
Q

Nursing considerations

A
  • Instruct patient not to self-medicate
  • Patient teaching about side effects
  • Med hx
  • Additive effects w/ other drugs
  • Diabetes
  • Liver disease
  • Gout
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