Vitamin B12 (Cyanocobalamin) Flashcards
1
Q
Pregnancy Category
A
- Pregnancy Category A
- C (parenteral)
2
Q
Mechanism of Action
A
- Essential for cell reproduction
- Maturation of RBCs
- Synthesis of DNA
- Maintenance of myelin sheath
3
Q
What is B12 used for?
A
Used to treat deficiency due to anemia, sprue, GI pathology, tapeworms, surgery
4
Q
deficiency syndrome
A
- Pernicious anemia: lack of intestinal factor needed to absorb vit. B12 from food (supplement must be given asan injection monthly for life.)
- Megaloblastic anemia
5
Q
Precautions
A
- heart disease
- anemia
- pulmonary disease
6
Q
Drug Interactions
A
- alcohol, neomycin –> decreased absorption
7
Q
Adverse Effects
A
- Facial swelling
- Diarrhea
- Itching
- Rash
8
Q
Serious Adverse Effects
A
- Anaphylactic shock
- Pulmonary edema
- Heart failure
- Sudden death
- Optic nerve neuropathy
9
Q
Nursing Responsiblities
A
- Educate patients that treatment for pernicious anemia will be life long
- Assess for alcohol use, malabsorption syndromes
