Vitamin B12 Metab Flashcards
What test is done for vitamin b12
Schilling test
Schilling test specifically checks
Folate and cobalamin absorption
Pernicious anaemia is an auto immune attack on
Gastric mucosa and
Parietal cells
Pernicious anaemia is characterized by the absence of
Hcl (achlodyria)
And IF INTINSIC FACTOR
Vitamin b12 causes
Megaloblastic anaemia
And neurotic problems
Vitamin b12 deficiency leading to neurotic problems is characterized by what action
B12 is a cofactor too the conversion of homocysteine to methionine
B12 is also used to produce myelin sheath and it’s absence leads to sclerosis
Vitamin b12 is transported in the body by
Transcobalamin
Vitamin b12 is absent in vegans because
B12 is only gotten from animal
Not from fruits cereal or vegetables
What transport b12 from the mouth to the duodenum
Heptocorrin
B12 digest where
Ileum
B12 forms a complex with IF by binding to what on IF
Cubulin