Vitamin B12 Metab Flashcards

1
Q

What test is done for vitamin b12

A

Schilling test

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2
Q

Schilling test specifically checks

A

Folate and cobalamin absorption

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3
Q

Pernicious anaemia is an auto immune attack on

A

Gastric mucosa and
Parietal cells

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4
Q

Pernicious anaemia is characterized by the absence of

A

Hcl (achlodyria)
And IF INTINSIC FACTOR

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5
Q

Vitamin b12 causes

A

Megaloblastic anaemia

And neurotic problems

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6
Q

Vitamin b12 deficiency leading to neurotic problems is characterized by what action

A

B12 is a cofactor too the conversion of homocysteine to methionine

B12 is also used to produce myelin sheath and it’s absence leads to sclerosis

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7
Q

Vitamin b12 is transported in the body by

A

Transcobalamin

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8
Q

Vitamin b12 is absent in vegans because

A

B12 is only gotten from animal

Not from fruits cereal or vegetables

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9
Q

What transport b12 from the mouth to the duodenum

A

Heptocorrin

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10
Q

B12 digest where

A

Ileum

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11
Q

B12 forms a complex with IF by binding to what on IF

A

Cubulin

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