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BIOCHEMISTRY 2 > Vitamin B12 deficiency, Methylmalonic Acidemia > Flashcards

Vitamin B12 deficiency, Methylmalonic Acidemia Flashcards

1
Q

Absorption in GI

A

intrinsic factor binds to vitamin B12 + enhances absorption by ileum

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2
Q

Symptoms

A 
anemia
depression
irritability
psychosis
abnormal sensation
changes in reflexes
poor muscle function
poor development + growth in children
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3
Q

Function of Vitamin B12

A

remethylation of homocysteine to methionine

isomerization of methylmalonyl CoA

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4
Q

Treatment

A

high dose B12 orally/ inter muscular injection

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5
Q

Problem of deficiency

A

FA accumulates

becomes incorporated into cell membranes

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BIOCHEMISTRY 2 (41 decks)

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