Ketolysis Flashcards
1
Q
Location
A
peripheral tissue
- skeletal muscle
- heart
- renal cortex
- brain
2
Q
Total energy yield
A
21,5 mol ATP
- 20 ATP from acetyl CoA
- 2,5 ATP from NADH
- 1GTP
3
Q
- D-B-hydroxybutyrate -> Acetoacetate
A
- oxidation
- NAD+ -> NADH
- enzyme: D-B_HYDROXYBUTYRATE DEHYDROGENASE
4
Q
- Acetoacetate -> Acetoacetyl CoA
A
Acetoacetate + Succinyl CoA -> Acetoacetyl CoA + Succinate
-enzyme: B-KETOACYL CoA TRANSFERASE
5
Q
- Acetoacetyl CoA -> 2x Acetyl CoA
A
-cleavage
+CoASH
-enzyme: THIOLASE
-used in TCA
