Galactose metabolism Flashcards
1
Q
Location
A
- in liver: converted to blood glucose in fasting and glycogen i fed state
- in tissue: glucose1P->glucose6P, goes to glycolysis
2
Q
Fate of UDP-galactose
A
- blood glucose/glycogen
- glucose1P
- synthesis of proteoglycans, glycolipids, glycoproteins
- milk(lactose) in mammary gland
- galactitol
3
Q
Galactose -> Galactose-1P
A
- phosphorylated by ATP
- enzyme: GALACTOKINASE
4
Q
Galactose 1P -> UDP-galactose
A
Galactose 1P + UDP -> Glucose 1P + UDP-galactose
-enzyme: GALACTOSE 1P URIDYLTRANSFERASE
5
Q
UDP-galactose -> UDP-glucose
A
- epimerization
- enzyme: UDP-GLUCOSE EPIMERASE