Vitamin B Flashcards
B-complex vitamins are ___________ soluble
Water soluble
Name of vitamin B1
Thiamin
Thiamin structure
Pyrimidine and Thiazole
What is the coenzyme form of Thiamin
TDP and TPP
Sources of Thiamin
Yeast
Pork
Legumes
Whole and enriched grains
Sunflower seeds
What are the 3 functions of Thiamin
Energy transformation
NADPH and Penrose
Nerve conduction
Energy transormation
NADPH and pentose
Nerve Conduction
Thiamin Deficiency
Beri Beri
Wear i KE-Korsakoff
Thiamin Toxicity
No UL
Large doses may help MSUD patients
Thiamin Assessment
What is the name of Vitamin B2
Riboflavin
What is the structure of VitB2/Riboflavin?
Flavin and ribitol
What are the 2 coenzyme forms of riboflavin/B2?
FMN and FAD
What are sources of Riboflavin/B2?
Milk
Dairy
Eggs
Meat
Legumes
Enriched grains
Riboflavin/B2 is sensitive to ___________
UV Light
What are the 6 function of Riboflavin/B2?
- Energy transformation
- Purine catabolism
- Vitamin B6 activation
- Folate activation
- Reduction of glutathione
- Niacin synthesis
What are the 3 Riboflavin/B2 deficiency ?
- Cheilosis
- Angular stomatitis
- Glossitis
Cheilosis
Angular stomatitis
Glositis
Who is at risk for Riboflavin/B2 deficiency?
- Elderly
- Some cancers
- Alcoholism
- Elevated metabolism
Does Riboflavin/B2 have a toxicity concern?
None reported
No UL
How do to assess riboflavin/B2?
Red cell glutathione reductase bc FAD is important in reducing glutathione
What is the name of Vitamin B3
Niacin
Structure of niacin/B3
Nicotinic acid and nicotinamide
What are the coenzyme forms of niacin B3?
NAD, NADH, NADP, NADPH
sources
MFP, enriched grains legumes
Synthesized from
Tryptophan
60mg try - 1mg nicain
Function
- Energy transformation
- HMP shunt
- Fatty acid synthesis
- Conversion of vitamin C, glutathione, folate to reduced states
- Lower cholesterol
How does niacin lower cholesterol
Niacin b3 deficiency
Pellagra
Dermatitis
Diarrhea
Dementia
Death
niacin B3 deficiency at risk
Isoniazid users reduces niacin synthesis
Low intake (alcoholics)
Elevated metabolism
Low protein and low tryptophan diet (corn)