Vitamin B Flashcards

1
Q

B-complex vitamins are ___________ soluble

A

Water soluble

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2
Q

Name of vitamin B1

A

Thiamin

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3
Q

Thiamin structure

A

Pyrimidine and Thiazole

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4
Q

What is the coenzyme form of Thiamin

A

TDP and TPP

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5
Q

Sources of Thiamin

A

Yeast
Pork
Legumes
Whole and enriched grains
Sunflower seeds

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6
Q

What are the 3 functions of Thiamin

A

Energy transformation
NADPH and Penrose
Nerve conduction

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7
Q

Energy transormation

A
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8
Q

NADPH and pentose

A
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9
Q

Nerve Conduction

A
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10
Q

Thiamin Deficiency

A

Beri Beri
Wear i KE-Korsakoff

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11
Q

Thiamin Toxicity

A

No UL
Large doses may help MSUD patients

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12
Q

Thiamin Assessment

A
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13
Q

What is the name of Vitamin B2

A

Riboflavin

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14
Q

What is the structure of VitB2/Riboflavin?

A

Flavin and ribitol

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15
Q

What are the 2 coenzyme forms of riboflavin/B2?

A

FMN and FAD

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16
Q

What are sources of Riboflavin/B2?

A

Milk
Dairy
Eggs
Meat
Legumes
Enriched grains

17
Q

Riboflavin/B2 is sensitive to ___________

18
Q

What are the 6 function of Riboflavin/B2?

A
  1. Energy transformation
  2. Purine catabolism
  3. Vitamin B6 activation
  4. Folate activation
  5. Reduction of glutathione
  6. Niacin synthesis
19
Q

What are the 3 Riboflavin/B2 deficiency ?

A
  1. Cheilosis
  2. Angular stomatitis
  3. Glossitis
20
Q

Cheilosis

21
Q

Angular stomatitis

22
Q

Glositis

23
Q

Who is at risk for Riboflavin/B2 deficiency?

A
  1. Elderly
  2. Some cancers
  3. Alcoholism
  4. Elevated metabolism
24
Q

Does Riboflavin/B2 have a toxicity concern?

A

None reported
No UL

25
How do to assess riboflavin/B2?
Red cell glutathione reductase bc FAD is important in reducing glutathione
26
What is the name of Vitamin B3
Niacin
27
Structure of niacin/B3
Nicotinic acid and nicotinamide
28
What are the coenzyme forms of niacin B3?
NAD, NADH, NADP, NADPH
29
sources
MFP, enriched grains legumes
30
Synthesized from
Tryptophan
31
60mg try - 1mg nicain
32
Function
1. Energy transformation 2. HMP shunt 3. Fatty acid synthesis 4. Conversion of vitamin C, glutathione, folate to reduced states 5. Lower cholesterol
33
How does niacin lower cholesterol
34
Niacin b3 deficiency
Pellagra Dermatitis Diarrhea Dementia Death
35
niacin B3 deficiency at risk
Isoniazid users reduces niacin synthesis Low intake (alcoholics) Elevated metabolism Low protein and low tryptophan diet (corn)