Fat Soluble Flashcards
Vitamin A structure
Retinol, retinal, retinoic acid, and retinyl esters
What are provitamin A?
carotenoids and Beta-carotene
Vitamin A animal source form
retinyl ester
Vitamin A retinyl ester sources
Liver
Fish liver oil
Egg yolk
Margarine/butter
Fortified milk
Vitamin A plant source form
provitamin A
Vitamin A carotenoid sources
Deep orange/yellow fruits and vegetables, dark leafy greens, broccoli
Vitamin A functions 7
- Vision
- Cell differentiation
- Growth
- Antioxidant
- Immune Function
- Bone growth
- Reproductive systems
Vitamin A role in vision
vitamin A is used to produce rhodopsin which allows for the detection of light
Vitamin A role in cell differentiation
through effects on gene expression
Vitamin A role in growth
stimulated by retinoic acid
Vitamin A role in antioxidant
carotenoids are involved decreasing oxidative stress; may decrease heart disease/cancer risk
What is rhodopsin
rhodopsin is found in the rods’ disks made up of retinal and opsin
What populations are at risk for vitamin A deficiency?
- Fat malabsorption
- Alcoholism
- Zinc deficiency
vitamin A toxicity symptoms
- Anorexia
- Skin discomfort
- Alopecia
- headache
Explain the rhodopsin cycle
light hits the retina on the back of the eye, rhodopsin in the rods cells is transformed and signals sent to brain, rhosopsin is cleaved into opsin and cis-retinal and conversion of cis-retinal to trans-retinal, tran-retinal is converted back to cis-retinal, cis-retinal reattaches to opsin to reform rhodopsin
Vitamin A deficiency symptoms
- Night blindness
- Bitot’s spot
- Xerophthalmia/keratomalacia
- Poor growth
Explain the vitamin A deficiency and its effect on night blindness
in darkness, after light passes, individual can only see a few few away.
what is bitot’s spots
white spots on eyes