B5, B7 Flashcards
1
Q
Pantothenic Acid B5 sources
A
- Found widely distributed (pantos means everywhere)
- Liver, meats, egg yolk, whole grains, mushrooms, broccoli,
avocados
2
Q
Pantothenic Acid B5 coenzyme
A
coenzyme A
3
Q
Pantothenic Acid B5 function
A
- Acyl group donor as part of coenzyme A
- Involved in:
- Kreb cycle (acetyl CoA, succinyl CoA)
- Gluconeogenesis (succinyl CoA)
- Fatty acid oxidation (fatty acyl CoA, acetyl CoA)
- Pyruvate and alpha-ketogulatarate decarboxylase
- Part of ________________________for fatty acid synthesis
4
Q
Pantothenic Acid B5 deficiency symptoms
A
- Only seen in severe malnutrition
*Symptoms:
* Burning feet, vomiting, fatigue, weakness
5
Q
Pantothenic ACid B5 at risk
A
- Alcoholics (low intake)
- diabetes mellitus (increased excretion)
- Inflammatory bowel disease (absorption problems)
6
Q
Pantothenic Acid B5 toxcity
A
- Not considered a problem, may cause gastrointestinal
distress and diarrhea - No UL
7
Q
Pantothenic Acid B5 assessment
A
- Plasma pantothenic acid
- Urinary pantothenic acid
8
Q
Biotin B7 sources
A
- Liver, soybeans, egg yolk, cereals, legumes, nuts
- Also produced by bacteria in colon
9
Q
Biotin B7 absorption
A
- A glycoprotein in raw egg whites called avidin
tightly binds to biotin and can prevent absorption, often
called egg white injury
10
Q
Biotin B7 functions
A
- Functions as a Carboxyl group carrier in:
- Carboxylation reactions
- Transcarboxylation involved in fermentation
- Decarboxylation involved in fermentation
11
Q
Biotin B7 deficiency *Populations at risk:
A
- Most often caused by ingestion of raw eggs
- GI disorders (decreased absorption)
- Alcoholics (decreased intake)
- Pregnant women
12
Q
Biotin B7 Symptiom of deficiency
A
- dermatitis, anorexia, depression, hallucination, alopecia
13
Q
Biotin B7 Toxicity
A
- No known toxic effects in humans
- No UL
14
Q
Biotin B7 assessment
A
*Blood/serum/plasma biotin
* Urinary biotin excretion